Tiedeman J J, Lippiello L, Connolly J F, Strates B S
Creighton-Nebraska Health Foundation, University of Nebraska, Omaha.
Clin Orthop Relat Res. 1990 Apr(253):279-86.
A noninvasive method was developed to assess fracture healing using optical densitometric methodology. Photometric measurements of osseous tissue density were based on illuminance or intensity of light, transmitted through standard roentgenograms. The method was tested in 6-mm tibial segmental defects and single-cut osteotomy defects in adult mongrel dogs. The lowest measureable bone density in the defect was compared to bending rigidity of the involved extremity. For both types of defect, an exponential relationship was found between the densitometric evaluation of the healing fracture gap and bending rigidity. This method proved superior to a roentgenographic scoring method and is capable of detecting small differences in mineral content using standard roentgenograms. The high correlation between densitometric evaluation and bone rigidity indicates this method has potential for use in the in vivo assessment of fracture healing.
开发了一种使用光学密度测定法评估骨折愈合的非侵入性方法。骨组织密度的光度测量基于透过标准X线片的光照度或光强度。该方法在成年杂种犬的6毫米胫骨节段性缺损和单切口截骨缺损中进行了测试。将缺损处可测量的最低骨密度与受累肢体的弯曲刚度进行比较。对于两种类型的缺损，在愈合骨折间隙的密度测定评估与弯曲刚度之间发现了指数关系。该方法被证明优于X线评分法，并且能够使用标准X线片检测矿物质含量的微小差异。密度测定评估与骨刚度之间的高度相关性表明该方法具有用于骨折愈合体内评估的潜力。
