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An observational study of bevacizumab-induced hypertension as a clinical biomarker of antitumor activity.贝伐珠单抗引起的高血压作为抗肿瘤活性的临床生物标志物的观察性研究。
Oncologist. 2011;16(9):1325-32. doi: 10.1634/theoncologist.2010-0002. Epub 2011 Aug 1.
2
Management of febrile neutropenia--a German prospective hospital cost analysis in lymphoproliferative disorders, non-small cell lung cancer, and primary breast cancer.发热性中性粒细胞减少症的管理——德国针对淋巴增生性疾病、非小细胞肺癌和原发性乳腺癌的前瞻性医院成本分析
Onkologie. 2011;34(5):241-6. doi: 10.1159/000327711. Epub 2011 Apr 26.
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Does telephone follow-up predict patient satisfaction and readmission?电话随访能否预测患者满意度和再入院率?
Popul Health Manag. 2011 Oct;14(5):249-55. doi: 10.1089/pop.2010.0045. Epub 2011 Apr 19.
4
Patient complexity and GPs' income under mixed remuneration.混合薪酬制下患者病情复杂程度与全科医生收入
Health Econ. 2012 Jun;21(6):619-32. doi: 10.1002/hec.1731. Epub 2011 Apr 12.
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Global cancer statistics.全球癌症统计数据。
CA Cancer J Clin. 2011 Mar-Apr;61(2):69-90. doi: 10.3322/caac.20107. Epub 2011 Feb 4.
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[The frequency of cancer in France in 2006, mortality trends since 1950, incidence trends since 1980 and analysis of the discrepancies between these trends].[2006年法国癌症发病率、1950年以来的死亡率趋势、1980年以来的发病率趋势以及这些趋势差异分析]
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Economic burden of haematological adverse effects in cancer patients: a systematic review.癌症患者血液学不良反应的经济负担:一项系统综述
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Oncologist. 2007 Apr;12(4):478-83. doi: 10.1634/theoncologist.12-4-478.
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Mortality, morbidity, and cost associated with febrile neutropenia in adult cancer patients.成年癌症患者发热性中性粒细胞减少症相关的死亡率、发病率和成本
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癌症化疗患者接受整合医学的成本效益。

Cost effectiveness of integrated medicine in patients with cancer receiving anticancer chemotherapy.

机构信息

Cochin Teaching Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.

出版信息

J Oncol Pract. 2012 Jul;8(4):205-10. doi: 10.1200/JOP.2011.000447. Epub 2012 Jun 5.

DOI:10.1200/JOP.2011.000447
PMID:23180982
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3396813/
Abstract

PURPOSE

Ambulatory chemotherapy is patient friendly but may result in toxicity-induced unscheduled hospitalizations (TIUHs). This emerging issue may increase health care costs. We studied the cost effectiveness of a hospital-home monitoring program based on systematic iterative telephone calls after chemotherapy.

PATIENTS AND METHODS

We retrospectively evaluated the rates of chemotherapy-induced unscheduled hospitalizations in patients who were treated in August 2008. Patients were contacted by telephone 1 day before chemotherapy and on the second and eighth days after undergoing chemotherapy. Costs associated with TIUHs were calculated and compared with those of a cohort concomitantly treated using the standard follow-up procedure.

RESULTS

A total of 259 patients entered the hospital-home monitoring program. They were compared with 86 patients who had similar characteristics but underwent the standard treatment and follow-up procedure. Inclusion in the hospital-home monitoring program resulted in patients experiencing TIUHs approximately half as frequently as patients in the other group (2.4% v 4.9%; P < .01). Patients in the program experienced TIUHs for a median length of stay of 4 days, representing a nonsignificant reduction in duration of hospitalization (P not significant). Consequently, through a two-fold reduction in TIUH annual incidence, this program represents a reduction in unscheduled hospitalizations per year of 383 days, decreasing hospital costs by €201.468 ($292,468) per year.

CONCLUSION

The hospital-home monitoring program is a cost-effective strategy for offering ambulatory chemotherapy treatment to patients with cancer. This program has become our standard procedure for ambulatory chemotherapy in patients with cancer.

摘要

目的

门诊化疗对患者友好,但可能导致毒性引起的非计划性住院(TIUH)。这一新兴问题可能会增加医疗保健成本。我们研究了一种基于化疗后系统迭代电话随访的医院-家庭监测计划的成本效益。

患者和方法

我们回顾性评估了 2008 年 8 月接受化疗的患者中化疗引起的非计划性住院率。患者在化疗前 1 天、化疗后第 2 天和第 8 天通过电话联系。计算了与 TIUH 相关的成本,并与同期接受标准随访程序治疗的患者进行了比较。

结果

共有 259 名患者入组医院-家庭监测计划。他们与 86 名具有相似特征但接受标准治疗和随访程序的患者进行了比较。入组医院-家庭监测计划的患者 TIUH 发生率约为对照组的一半(2.4%对 4.9%;P<.01)。该计划中患者的 TIUH 住院时间中位数为 4 天,表明住院时间无显著缩短(P 无统计学意义)。因此,通过将 TIUH 年发生率降低两倍,该计划每年可减少 383 天的非计划性住院,每年降低医院费用 201468 欧元(292468 美元)。

结论

医院-家庭监测计划是为癌症患者提供门诊化疗治疗的一种具有成本效益的策略。该计划已成为我们为癌症患者提供门诊化疗的标准程序。