Locked nucleic acid and aptamers.
作者信息
Karlsen Kasper K, Wengel Jesper
机构信息
Nucleic Acid Center, Department of Physics, Chemistry, and Pharmacy, University of Southern Denmark, Odense M, Denmark.
出版信息
Nucleic Acid Ther. 2012 Dec;22(6):366-70. doi: 10.1089/nat.2012.0382.
Abstract
摘要
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本文引用的文献
1
Efficient reverse transcription using locked nucleic acid nucleotides towards the evolution of nuclease resistant RNA aptamers.利用锁核酸核苷酸进行高效逆转录，以进化出耐核酸酶的 RNA 适体。
PLoS One. 2012;7(4):e35990. doi: 10.1371/journal.pone.0035990. Epub 2012 Apr 25.
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Synthetic genetic polymers capable of heredity and evolution.能够遗传和进化的合成遗传聚合物。
Science. 2012 Apr 20;336(6079):341-4. doi: 10.1126/science.1217622.
3
One round of SELEX for the generation of DNA aptamers directed against KLK6.针对 KLK6 生成 DNA 适体的 SELEX 筛选的一轮实验。
Biol Chem. 2012 Apr;393(5):343-53. doi: 10.1515/hsz-2011-0253.
4
Properties of an LNA-modified ricin RNA aptamer.LNA 修饰的蓖麻 RNA 适体的性质。
Biochem Biophys Res Commun. 2012 Mar 2;419(1):60-5. doi: 10.1016/j.bbrc.2012.01.127. Epub 2012 Feb 3.
5
RNA aptamer evolution: two decades of SELEction.RNA适配体的进化：二十年的指数富集配体系统进化技术
Int J Mol Sci. 2011;12(12):9155-71. doi: 10.3390/ijms12129155. Epub 2011 Dec 8.
6
Enzymatic recognition of 2'-modified ribonucleoside 5'-triphosphates: towards the evolution of versatile aptamers.酶对 2'-修饰核苷 5'-三磷酸的识别：向着多功能适体的进化。
Chembiochem. 2012 Jan 2;13(1):19-25. doi: 10.1002/cbic.201100648. Epub 2011 Dec 12.
7
A multivalent DNA aptamer specific for the B-cell receptor on human lymphoma and leukemia.一种针对人淋巴瘤和白血病 B 细胞受体的多价 DNA 适体。
Nucleic Acids Res. 2011 Mar;39(6):2458-69. doi: 10.1093/nar/gkq996. Epub 2010 Oct 28.
8
Aptamers as therapeutics.适配子疗法。
Nat Rev Drug Discov. 2010 Jul;9(7):537-50. doi: 10.1038/nrd3141.
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Locked nucleic acids: promising nucleic acid analogs for therapeutic applications.锁核酸：有前途的治疗应用核酸类似物。
Chem Biodivers. 2010 Mar;7(3):536-42. doi: 10.1002/cbdv.200900343.
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Effect of 3'-end capping of aptamer with various 2',4'-bridged nucleotides: Enzymatic post-modification toward a practical use of polyclonal aptamers.各种 2',4'-桥连核苷酸对适体 3'端加帽的影响：多克隆适体实际应用的酶后修饰。
Bioorg Med Chem Lett. 2010 Mar 1;20(5):1626-9. doi: 10.1016/j.bmcl.2010.01.028. Epub 2010 Jan 22.
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