Department of Dermatology, Far Eastern Memorial Hospital, Taipei, Taiwan.
J Am Acad Dermatol. 2013 Aug;69(2):e69-77. doi: 10.1016/j.jaad.2012.09.046. Epub 2012 Nov 20.
Although female pattern hair loss (FPHL) has been considered simply the female counterpart of male pattern hair loss in men, the risk factors may differ.
We sought to evaluate factors associated with FPHL and to estimate its prevalence in women.
In total, 26,226 subjects aged 30 years and older participated in a cross-sectional survey. Ludwig and Norwood classifications were used to assess the degree of hair loss. Information on possible risk factors for FPHL was collected using a questionnaire interview.
The prevalence of FPHL (Ludwig grade >I) for all ages was 11.8% (95% CI 11.5%-12.2%), increasing with advancing age. After controlling for age and family history, statistically significant associations were noted between FPHL and high fasting glucose (odds ratio [OR] 1.15, 95% confidence interval [CI] 1.04-1.28), fewer childbirths (OR 1.24, 95% CI 1.12-1.38), breast-feeding (OR 0.88, 95% CI 0.78-0.98), oral contraceptive use (OR 1.21, 95% CI 1.01-1.45), and ultraviolet exposure more than 16 hours per week (OR 1.12, 95% CI 1.02-1.22).
The validity and reliability of FPHL classification may be not perfect in this survey and may need to be verified. Information on family history may be still subject to recall bias.
Risk factors for FPHL and male androgenic alopecia may differ.
虽然女性型脱发(FPHL)被认为只是男性型脱发的女性对应,但风险因素可能不同。
我们旨在评估与 FPHL 相关的因素,并估计女性 FPHL 的患病率。
共有 26226 名年龄在 30 岁及以上的受试者参加了横断面调查。使用 Ludwig 和 Norwood 分类来评估脱发程度。使用问卷访谈收集可能与 FPHL 相关的信息。
所有年龄段 FPHL(Ludwig 分级>I)的患病率为 11.8%(95%CI 11.5%-12.2%),随年龄增长而增加。在控制年龄和家族史后,FPHL 与空腹高血糖(比值比 [OR] 1.15,95%置信区间 [CI] 1.04-1.28)、生育次数少(OR 1.24,95%CI 1.12-1.38)、母乳喂养(OR 0.88,95%CI 0.78-0.98)、口服避孕药使用(OR 1.21,95%CI 1.01-1.45)和每周接受紫外线照射超过 16 小时(OR 1.12,95%CI 1.02-1.22)呈统计学显著相关。
本调查中 FPHL 分类的有效性和可靠性可能并不完美,需要进一步验证。家族史信息可能仍存在回忆偏倚。
FPHL 和男性雄激素性脱发的风险因素可能不同。