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绝经后妇女女性型脱发的患病率:一项横断面研究。

Prevalence of female pattern hair loss in postmenopausal women: a cross-sectional study.

机构信息

Menopause Research Group, Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand.

Department of Obstetrics and Gynecology, Chao Phraya Abhaibhubejhr Hospital, Prachin Buri, Thailand.

出版信息

Menopause. 2022 Feb 14;29(4):415-420. doi: 10.1097/GME.0000000000001927.

Abstract

OBJECTIVE

To identify the prevalence of female pattern hair loss (FPHL), hair characteristics, and associated factors in healthy postmenopausal women.

METHODS

Two hundred postmenopausal women aged 50 to 65 years were recruited. Each participant was evaluated for FPHL according to Ludwig's classification using standardized global photography in all six views and trichoscopy for hair density and diameter. Three dermatologists re-evaluated all pictures for confirmation of FPHL. The time since menopause, levels of scalp sebum, serum testosterone, estradiol, thyroid stimulating hormone, and hemoglobin; family history of hair loss, as well as an evaluation of low self-esteem were evaluated. Women who underwent recent hair loss treatments were excluded. We used simple and multivariable logistic regression analysis to identify the factors affecting FPHL.

RESULTS

In total, 178 postmenopausal women were evaluated for hair-loss patterns. The average age and time since menopause were 58.8±4.1 and 9.2 ± 5.6 years, respectively. The prevalence of FPHL was 52.2% (95% CI, 44.6-59.8). Severity of FPHL by Ludwig grades I, II, and III was 73.2% (95% CI, 62.9-81.8), 22.6% (95% CI, 14.6-32.4), and 4.3% (95% CI, 1.2-10.7), respectively. Logistic regression analysis revealed that age, time since menopause, and body mass index were all significantly associated with FPHL. After adjusting for age and family history of FPHL, only body mass index ≥25 kg/m2 was significantly associated with FPHL (adjusted OR = 2.65, 95% CI, 1.23-5.70). Conclusion: The prevalence of FPHL was high in postmenopausal women, raising the need for hair loss awareness in menopause clinics. Early detection and proper treatment of FPHL may increase the quality of life in postmenopausal women.

摘要

目的

确定健康绝经后女性中女性型脱发(FPHL)的患病率、头发特征和相关因素。

方法

招募了 200 名 50 至 65 岁的绝经后女性。每位参与者均根据 Ludwig 分类使用标准的全头皮摄影在六个视图和毛发密度和直径的 trichoscopy 进行 FPHL 评估。三位皮肤科医生对所有图片进行了重新评估,以确认 FPHL。评估了绝经时间、头皮皮脂水平、血清睾酮、雌二醇、促甲状腺激素和血红蛋白;脱发的家族史,以及自尊心评估。排除最近接受过脱发治疗的女性。我们使用简单和多变量逻辑回归分析来确定影响 FPHL 的因素。

结果

共有 178 名绝经后妇女接受了脱发模式评估。平均年龄和绝经时间分别为 58.8±4.1 岁和 9.2 ± 5.6 年。FPHL 的患病率为 52.2%(95%CI,44.6-59.8)。按 Ludwig 分级 I、II 和 III 级的 FPHL 严重程度分别为 73.2%(95%CI,62.9-81.8)、22.6%(95%CI,14.6-32.4)和 4.3%(95%CI,1.2-10.7)。逻辑回归分析表明,年龄、绝经时间和体重指数均与 FPHL 显著相关。在校正年龄和 FPHL 的家族史后,仅体重指数≥25kg/m2 与 FPHL 显著相关(调整后的 OR=2.65,95%CI,1.23-5.70)。结论:绝经后妇女 FPHL 的患病率较高,这就需要在更年期诊所提高对脱发的认识。早期发现和适当治疗 FPHL 可能会提高绝经后妇女的生活质量。

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