Pometta D, Micheli H
Schweiz Med Wochenschr. 1979 Dec 15;109(48):1926-30.
VLDL triglycerides were increased both in obese patients and obese controls. In lean CHD patients the VLDL triglycerides were higher than in lean controls but lower than in obese CHD patients. CHD patients had lower HDL cholesterol than controls. The lowest HDL cholesterol was observed when VLDL triglycerides were high in both CHD patients and controls. However, the differences in HDL cholesterol between CHD patients and controls with low VLDL triglycerides were more marked. It appears that factors other than VLDL triglycerides may also contribute to the low HDL cholesterol observed in CHD patients. Serum cholesterol and triglycerides did not reflect the more subtle changes occurring in the lipoprotein lipids of CHD patients.
肥胖患者和肥胖对照组的极低密度脂蛋白甘油三酯均升高。在瘦的冠心病患者中,极低密度脂蛋白甘油三酯高于瘦的对照组,但低于肥胖的冠心病患者。冠心病患者的高密度脂蛋白胆固醇低于对照组。当冠心病患者和对照组的极低密度脂蛋白甘油三酯都很高时,观察到的高密度脂蛋白胆固醇最低。然而,极低密度脂蛋白甘油三酯水平低的冠心病患者和对照组之间高密度脂蛋白胆固醇的差异更为明显。似乎除了极低密度脂蛋白甘油三酯之外的其他因素也可能导致冠心病患者中观察到的高密度脂蛋白胆固醇降低。血清胆固醇和甘油三酯并未反映出冠心病患者脂蛋白脂质中发生的更细微变化。