Robles Raya Purificación, de Frutos Echaniz Elena, Moreno Millán Nemesio, Mas Casals Ariadna, Sánchez Callejas Andrea, Morató Agustí M Luisa
Grupo de Trabajo en Prevención de las Enfermedades Infecciosas, Sociedad Catalana de Medicina de Familia y Comunitaria (CAMFIC), Barcelona, España.
Aten Primaria. 2013 Apr;45(4):216-21. doi: 10.1016/j.aprim.2012.10.006. Epub 2012 Nov 23.
Odontogenic infections account for 10% of all antibiotic prescriptions in Spain. Despite the frequency and importance of these infections, there is often confusion between prophylaxis and treatment. The oral cavity is a complex ecosystem made up of over 500 bacterial species. It is essential to take the medical history, examine each infection, and know about previous illnesses that could change our therapeutic and/or prophylactic attitude. The use of prophylaxis with antibiotics in patients at risk of infective endocarditis has been accepted for many years. Nowadays this is being restricted, and in many cases the risks of taking preventive antibiotics outweigh its benefits. There are no serious studies to determine the best antibiotic and its dosage, thus the Spanish consensus guidelines have to be followed. It is not known how the misuse of antibiotics influences bacterial resistance, not only on pathogen strains, but also on the common oral flora.
在西班牙,牙源性感染占所有抗生素处方的10%。尽管这些感染很常见且很重要,但在预防和治疗之间常常存在混淆。口腔是一个由500多种细菌组成的复杂生态系统。了解病史、检查每种感染情况以及知晓可能改变我们治疗和/或预防态度的既往疾病至关重要。多年来,对于有感染性心内膜炎风险的患者使用抗生素进行预防已被认可。如今,这种做法正在受到限制,而且在许多情况下,服用预防性抗生素的风险超过了其益处。目前尚无确定最佳抗生素及其剂量的严谨研究,因此必须遵循西班牙的共识指南。尚不清楚抗生素的滥用如何影响细菌耐药性,这不仅涉及病原菌菌株,还涉及常见的口腔菌群。