Gorin N C, Najman A, Parrot G, Duhamel G
Sem Hop. 1979;55(35-36):1581-4.
A 53 years old female patient with plasma cell leukemia (more than 90% plasma cells in the peripheral blood, and an absolute plasma cell count reaching 147,000/mm3) is described. Electrophoresis and immunoelectrophoresis of serum and concentrated urine did not reveal any paraprotein. No surface immunoglobin has been detected on plasma cell cytoplasmic membranes. The presence of intracytoplasmic kappa light chains has been demonstrated by immunofluorescence and electron microscopy using the immunoperoxydase technique.
描述了一名53岁的女性浆细胞白血病患者(外周血中浆细胞超过90%,绝对浆细胞计数达到147,000/mm³)。血清和浓缩尿的电泳及免疫电泳未发现任何副蛋白。在浆细胞质膜上未检测到表面免疫球蛋白。通过使用免疫过氧化物酶技术的免疫荧光和电子显微镜证实了胞质内κ轻链的存在。