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眼震视图与颈性前庭诱发肌源性电位在诊断上半规管裂综合征中的比较。

Ocular versus cervical VEMPs in the diagnosis of superior semicircular canal dehiscence syndrome.

机构信息

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA.

出版信息

Otol Neurotol. 2013 Jan;34(1):121-6. doi: 10.1097/MAO.0b013e31827136b0.

Abstract

OBJECTIVES

To determine whether cervical vestibular evoked myogenic potential (cVEMP) thresholds or ocular VEMP (oVEMP) amplitudes are more sensitive and specific in the diagnosis of superior semicircular canal dehiscence syndrome (SCDS).

STUDY DESIGN

Prospective case-control study.

SETTING

Tertiary referral center.

SUBJECTS AND METHODS

Twenty-nine patients with SCDS (mean age 48 yr; range, 31-66 yr) and 25 age-matched controls (mean age 48 yr; range, 30-66 yr).

INTERVENTION(S): cVEMP and oVEMP in response to air-conducted sound. All patients underwent surgery for repair of SCDS.

MAIN OUTCOME MEASURE(S): cVEMP thresholds; oVEMP n10 and peak-to-peak amplitudes.

RESULTS

cVEMP threshold results showed sensitivity and specificity ranging from 80% to 100% for the diagnosis of SCDS. In contrast, oVEMP amplitudes demonstrated sensitivity and specificity greater than 90%.

CONCLUSION

oVEMP amplitudes are superior to cVEMP thresholds in the diagnosis of SCDS.

摘要

目的

确定颈性前庭诱发肌源性电位(cVEMP)阈值或眼性前庭诱发肌源性电位(oVEMP)振幅在诊断上半规管裂综合征(SCDS)中哪个更敏感和特异。

研究设计

前瞻性病例对照研究。

设置

三级转诊中心。

受试者和方法

29 例 SCDS 患者(平均年龄 48 岁;范围,31-66 岁)和 25 例年龄匹配的对照组(平均年龄 48 岁;范围,30-66 岁)。

干预措施

空气传导声音刺激下的 cVEMP 和 oVEMP。所有患者均接受 SCDS 修复手术。

主要观察指标

cVEMP 阈值;oVEMP n10 和峰峰值振幅。

结果

cVEMP 阈值结果显示,诊断 SCDS 的灵敏度和特异度范围为 80%-100%。相比之下,oVEMP 振幅的灵敏度和特异度均大于 90%。

结论

oVEMP 振幅在诊断 SCDS 方面优于 cVEMP 阈值。

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