Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287-0910, USA.
Otol Neurotol. 2010 Jul;31(5):793-802. doi: 10.1097/MAO.0b013e3181e3d60e.
To determine the test-retest reliability and age-related trends of the cervical and ocular vestibular evoked myogenic potential (cVEMP and oVEMP, respectively) responses to air-conducted sound and bone-conducted vibration stimulation.
Prospective study.
Tertiary referral center.
Fifty-three healthy adults with no hearing or vestibular deficits.
INTERVENTION(S): All subjects underwent cVEMP and oVEMP testing in response to sounds (0.1-ms clicks and 500-Hz tone bursts) and vibration (midline forehead taps at the hairline, Fz, with a reflex hammer and a Brüel & Kjaer Mini-Shaker Type 4810). Twelve subjects underwent an additional testing session that was conducted at a mean of 10 weeks after the first one.
MAIN OUTCOME MEASURE(S): Test-retest reliability for VEMP response parameters (latency, peak-to-peak amplitude, and asymmetry ratio) were assessed using the intraclass correlation coefficient (ICC).
: oVEMP amplitudes had excellent test-retest reliability (ICC > 0.75) for all 4 stimuli; cVEMP amplitudes had excellent reliability for hammer taps and fair-to-good reliability for other stimuli. oVEMP asymmetry ratios had excellent reliability for clicks and fair-to-good reliability (ICC = 0.4-0.75) for other stimuli; cVEMP asymmetry ratios had fair-to-good reliability for clicks and hammer taps. Older subjects (>50 years old) were found to have significantly decreased cVEMP amplitudes in response to clicks, tones, and taps with a Mini-Shaker and significantly decreased oVEMP amplitudes in response to clicks, tones, and taps with a reflex hammer. No age-related changes were found for latencies or asymmetry ratios.
Overall, oVEMP response parameters demonstrated better test-retest reliability than cVEMP response parameters, but oVEMPs and cVEMPs had similar age-related changes.
确定经空气传导声音和骨传导振动刺激的颈和眼前庭诱发肌源性电位（cVEMP 和 oVEMP）反应的复测信度和与年龄相关的趋势。
前瞻性研究。
三级转诊中心。
53 名无听力或前庭缺损的健康成年人。
所有受试者均接受 cVEMP 和 oVEMP 测试，以响应声音（0.1 毫秒的点击声和 500Hz 纯音）和振动（中线上额部敲击，Fz，使用反射锤和 Bruel & Kjaer Mini-Shaker Type 4810）。12 名受试者在第一次测试后平均 10 周进行了额外的测试。
使用组内相关系数（ICC）评估 VEMP 反应参数（潜伏期、峰峰值幅度和不对称比）的复测信度。
oVEMP 幅度对于所有 4 种刺激均具有极好的复测信度（ICC>0.75）；cVEMP 幅度对于敲击锤刺激具有极好的可靠性，对于其他刺激具有良好至中等的可靠性。oVEMP 不对称比对于点击刺激具有极好的可靠性，对于其他刺激具有良好至中等的可靠性（ICC=0.4-0.75）；cVEMP 不对称比对于点击刺激和敲击锤刺激具有良好至中等的可靠性。>50 岁的老年受试者在对敲击声、音调、和 Mini-Shaker 刺激的 cVEMP 反应中表现出明显降低的振幅，在对敲击声、音调、和反射锤刺激的 oVEMP 反应中表现出明显降低的振幅。未发现潜伏期或不对称比与年龄相关的变化。
总体而言，oVEMP 反应参数的复测信度优于 cVEMP 反应参数，但 oVEMP 和 cVEMP 具有相似的与年龄相关的变化。
