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X射线辐射与静磁场对大鼠淋巴细胞活性氧的体外联合效应

Combined effect of X-ray radiation and static magnetic fields on reactive oxygen species in rat lymphocytes in vitro.

作者信息

Politański Piotr, Rajkowska Elźbieta, Brodecki Marcin, Bednarek Andrzej, Zmyślony Marek

机构信息

Nofer Institute of Occupational Medicine, 91-348 Lodz, Poland.

出版信息

Bioelectromagnetics. 2013 May;34(4):333-6. doi: 10.1002/bem.21767. Epub 2012 Nov 26.


DOI:10.1002/bem.21767
PMID:23184469
Abstract

The aim of this study was to investigate the effect of static magnetic fields (SMF) on reactive oxygen species induced by X-ray radiation. The experiments were performed on lymphocytes from male albino Wistar rats. After exposure to 3 Gy X-ray radiation (with a dose rate of 560 mGy/min) the measurement of intracellular reactive oxygen species in lymphocytes, using a fluorescent probe, was done before exposure to the SMF, and after 15 min, 1 and 2 h of exposure to the SMF or a corresponding incubation time. For SMF exposure, 0 mT (50 µT magnetic field induction opposite to the geomagnetic field) and 5 mT fields were chosen. The trend of SMF effects for 0 mT was always opposite that of 5 mT. The first one decreased the rate of fluorescence change, while the latter one increased it.

摘要

本研究的目的是探讨静磁场(SMF)对X射线辐射诱导的活性氧的影响。实验采用雄性白化Wistar大鼠的淋巴细胞进行。在暴露于3 Gy X射线辐射(剂量率为560 mGy/min)后,使用荧光探针在暴露于SMF之前以及暴露于SMF 15分钟、1小时和2小时后或相应的孵育时间后,对淋巴细胞内的活性氧进行测量。对于SMF暴露,选择了0 mT(与地磁场相反的50 μT磁场感应强度)和5 mT的磁场。0 mT的SMF效应趋势总是与5 mT的相反。前者降低了荧光变化率,而后者则提高了荧光变化率。

相似文献

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[2]
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Br J Radiol. 2023-3

[3]
Biological effects of static magnetic field exposure in the context of MR-guided radiotherapy.

Br J Radiol. 2019-2

[4]
Rotations of macromolecules affect nonspecific biological responses to magnetic fields.

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[5]
Biological effects of the hypomagnetic field: An analytical review of experiments and theories.

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[6]
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