Politański Piotr, Rajkowska Elźbieta, Brodecki Marcin, Bednarek Andrzej, Zmyślony Marek
Nofer Institute of Occupational Medicine, 91-348 Lodz, Poland.
Bioelectromagnetics. 2013 May;34(4):333-6. doi: 10.1002/bem.21767. Epub 2012 Nov 26.
The aim of this study was to investigate the effect of static magnetic fields (SMF) on reactive oxygen species induced by X-ray radiation. The experiments were performed on lymphocytes from male albino Wistar rats. After exposure to 3 Gy X-ray radiation (with a dose rate of 560 mGy/min) the measurement of intracellular reactive oxygen species in lymphocytes, using a fluorescent probe, was done before exposure to the SMF, and after 15 min, 1 and 2 h of exposure to the SMF or a corresponding incubation time. For SMF exposure, 0 mT (50 µT magnetic field induction opposite to the geomagnetic field) and 5 mT fields were chosen. The trend of SMF effects for 0 mT was always opposite that of 5 mT. The first one decreased the rate of fluorescence change, while the latter one increased it.
本研究的目的是探讨静磁场(SMF)对X射线辐射诱导的活性氧的影响。实验采用雄性白化Wistar大鼠的淋巴细胞进行。在暴露于3 Gy X射线辐射(剂量率为560 mGy/min)后,使用荧光探针在暴露于SMF之前以及暴露于SMF 15分钟、1小时和2小时后或相应的孵育时间后,对淋巴细胞内的活性氧进行测量。对于SMF暴露,选择了0 mT(与地磁场相反的50 μT磁场感应强度)和5 mT的磁场。0 mT的SMF效应趋势总是与5 mT的相反。前者降低了荧光变化率,而后者则提高了荧光变化率。
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