Wu Ming-Hsun, Wang Ming-Yang, Yang Ching-Yao, Lee Po-Huang, Lin Ming-Tsan
Department of General Surgery, National Taiwan University Hospital, Taipei, Taiwan.
Hepatogastroenterology. 2013 May;60(123):439-42. doi: 10.5754/hge12944.
BACKGROUND/AIMS: It has been a matter of debate whether the advantage of gasless laparoscope setting is obvious when compared with the conventional operation. Thus, we compare the systemic response of proinflammatory markers and the adhesion molecules in serum levels after surgery between these two procedures.
There were 23 patients in the gasless laparoscopy (GL) group, and 12 patients in the open surgery (OS) group.
The created wound length was smaller in the GL group (5.3±0.3cm vs. 8.9±0.5cm), the post operative recovery including the visual analog pain score on op day and day 1, flatus day, and hospital stay were also shown less in GL group. The levels of IL-6, IL-8 and ICAM were significantly lower in the GL group.
Immune response is less in gasless laparoscopy-assisted gastrectomy (GLAG) when compared with traditional approach, and the difference may have effects on the post operative recovery.
背景/目的：与传统手术相比，免气腹腹腔镜手术的优势是否明显一直存在争议。因此，我们比较了这两种手术术后血清中促炎标志物和黏附分子的全身反应。
免气腹腹腔镜手术（GL）组有23例患者，开放手术（OS）组有12例患者。
GL组的手术切口长度更小（5.3±0.3cm对8.9±0.5cm），GL组术后恢复情况，包括术后当天及第1天的视觉模拟疼痛评分、排气时间和住院时间也更优。GL组白细胞介素-6、白细胞介素-8和细胞间黏附分子水平显著更低。
与传统手术方式相比，免气腹腹腔镜辅助胃切除术（GLAG）的免疫反应更小，这种差异可能会影响术后恢复。
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