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腹腔镜下非切割 Roux-en-Y 胃空肠吻合术在远端胃切除术后应用加速康复外科的价值。

Application value of enhanced recovery after surgery for total laparoscopic uncut Roux-en-Y gastrojejunostomy after distal gastrectomy.

机构信息

Department of General Surgery, The Second Hospital of Shandong University, Jinan 250033, Shandong Province, China.

出版信息

World J Gastroenterol. 2018 Jan 28;24(4):504-510. doi: 10.3748/wjg.v24.i4.504.

Abstract

AIM

To evaluate the safety and feasibility of enhanced recovery after surgery (ERAS) for total laparoscopic uncut Roux-en-Y gastrojejunostomy after distal gastrectomy.

METHODS

The clinical data of 42 patients who were divided into an ERAS group ( = 20) and a control group ( = 22) were collected. The observed indicators included operation conditions, postoperative clinical indexes, and postoperative serum stress indexes. Measurement data following a normal distribution are presented as mean ± SD and were analyzed by -test. Count data were analyzed by χ test.

RESULTS

The operative time, volume of intraoperative blood loss, and number of patients with conversion to open surgery were not significantly different between the two groups. Postoperative clinical indexes, including the time to initial anal exhaust, time to initial liquid diet intake, time to out-of-bed activity, and duration of hospital stay of patients without complications, were significantly different between the two groups ( = 2.045, 8.685, 2.580, and 4.650, respectively, < 0.05 for all). However, the time to initial defecation, time to abdominal drainage-tube removal, and the early postoperative complications were not significantly different between the two groups. Regarding postoperative complications, on the first and third days after the operation, the white blood cell count (WBC) and C reactive protein (CRP) and interleukin-6 (IL-6) levels in the ERAS group were significantly lower than those in the control group.

CONCLUSION

The perioperative ERAS program for total laparoscopic uncut Roux-en-Y gastrojejunostomy after distal gastrectomy is safe and effective and should be popularized. Additionally, this program can also reduce the duration of hospital stay and improve the degree of comfort and satisfaction of patients.

摘要

目的

评估腹腔镜下非切割 Roux-en-Y 胃空肠吻合术在远端胃癌根治术后快速康复外科(ERAS)中的安全性和可行性。

方法

收集 42 例行腹腔镜下非切割 Roux-en-Y 胃空肠吻合术的远端胃癌根治术患者的临床资料,分为 ERAS 组(n = 20)和对照组(n = 22)。观察指标包括手术情况、术后临床指标和术后血清应激指标。正态分布的计量资料以均数 ± 标准差表示,采用 t 检验进行分析。计数资料采用 χ 检验。

结果

两组患者的手术时间、术中出血量、中转开腹例数差异均无统计学意义。术后临床指标中,无并发症患者的首次肛门排气时间、首次流质饮食时间、下床活动时间和住院时间差异均有统计学意义(t = 2.045、8.685、2.580、4.650,均 P < 0.05)。但首次排便时间、引流管拔除时间和早期术后并发症差异无统计学意义。术后并发症方面,ERAS 组患者在术后第 1、3 天的白细胞计数(WBC)、C 反应蛋白(CRP)和白细胞介素-6(IL-6)水平均低于对照组,差异均有统计学意义(t = 2.321、3.082、2.422,均 P < 0.05)。

结论

腹腔镜下非切割 Roux-en-Y 胃空肠吻合术在远端胃癌根治术后应用 ERAS 方案安全、有效,值得推广。同时,该方案还可以缩短患者的住院时间,提高患者舒适度和满意度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de7e/5787785/298b37c4ecd8/WJG-24-504-g001.jpg

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