Willi B, Kook P H, Quante S, Boretti F, Sieber-Ruckstuhl N S, Grest P, Scherrer O, Riond B, Hofmann-Lehmann R, Nussberger J, Reusch C E
Klinik für Kleintiermedizin und Veterinärmedizinisches Labor der Universität Zürich.
Schweiz Arch Tierheilkd. 2012 Dec;154(12):529-37. doi: 10.1024/0036-7281/a000402.
Primary hyperaldosteronism is a clinical syndrome characterized by an elevated aldosterone secretion by the adrenals. The present case series describes 7 cats with primary hyperaldosteronism, which were presented between 2002 and 2011. Common clinical symptoms were weakness, anorexia, cervical ventroflexion and blindness. All cats showed hypokalemia. In 6 cats, blood pressure was determined: 5 cats showed hypertension, of which 4 animals exhibited retinal detachment and blindness. In the ultrasonographic examination, unilateral adrenomegaly was present in 6 cats whereas one animal showed normal adrenals. In 4 cats, the serum aldosterone concentration was above the reference range. Five cats underwent unilateral adrenalectomy, which was accomplished uneventfully and returned the electrolytes back to normal. Histopathological examination of the adrenals revealed 2 carcinomas and 4 adenomas; one cat with ultrasonographic normal adrenals exhibited bilateral nodular hyperplasia.
原发性醛固酮增多症是一种临床综合征，其特征为肾上腺醛固酮分泌增加。本病例系列描述了2002年至2011年间出现的7只患有原发性醛固酮增多症的猫。常见临床症状为虚弱、厌食、颈部腹曲和失明。所有猫均表现为低钾血症。对6只猫测定了血压：5只猫表现为高血压，其中4只动物出现视网膜脱离和失明。超声检查显示，6只猫存在单侧肾上腺肿大，而1只动物的肾上腺正常。4只猫的血清醛固酮浓度高于参考范围。5只猫接受了单侧肾上腺切除术，手术顺利完成，电解质恢复正常。肾上腺组织病理学检查发现2例癌和4例腺瘤；1只超声检查肾上腺正常的猫表现为双侧结节性增生。
