Chen Ping, Wan Yigang, Wang Chaojun, Zhao Qing, Wei Qingxue, Tu Yue, Yin Xuejiao
Department of Traditional Chinese Medicine, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, China.
Zhongguo Zhong Yao Za Zhi. 2012 Aug;37(15):2252-6.
Abelmoschus manihot (AM) is a medicinal plant rich in twenty kinds of separated active bio-components including flavones, polysaccharides, trannic acid, and long chain hydrocarbons. Among these, total flavones of A. manihot (TFA) are the major active component. In this review, the mechanisms of Huangkui capsule will be discussed as a preparation of AM to treat chronic kidney disease (CKD) by improving immunological reaction, inflammation, renal fibrosis, and renal tubular epithelial injury. Additionally, it has been reported that Huangkui capsule can ameliorate some clinical symptoms, proteinuria, hematuria, and renal function in patients with common CKD, such as nephrotic syndrome, diabetic nephropathy, Henoch-Schönlein purpura nephritis, IgA nephropathy, and membranous nephropathy.
黄蜀葵是一种药用植物，富含二十种分离出的活性生物成分，包括黄酮类、多糖、反式酸和长链碳氢化合物。其中，黄蜀葵总黄酮（TFA）是主要活性成分。在这篇综述中，将讨论黄葵胶囊作为一种黄蜀葵制剂，通过改善免疫反应、炎症、肾纤维化和肾小管上皮损伤来治疗慢性肾脏病（CKD）的机制。此外，据报道，黄葵胶囊可以改善常见CKD患者的一些临床症状、蛋白尿、血尿和肾功能，如肾病综合征、糖尿病肾病、过敏性紫癜性肾炎、IgA肾病和膜性肾病。
