Department of Medical Parasitology and Entomology, School of Medicine, Catholic University of Health and Allied Sciences, Mwanza, Tanzania.
Parasit Vectors. 2012 Nov 28;5:274. doi: 10.1186/1756-3305-5-274.
In Tanzania, the first cases of schistosomiasis were reported in the early 19th century. Since then, various studies have reported prevalences of up to 100% in some areas. However, for many years, there have been no sustainable control programmes and systematic data from observational and control studies are very limited in the public domain. To cover that gap, the present article reviews the epidemiology, malacology, morbidity, and the milestones the country has made in efforts to control schistosomiasis and discusses future control approaches. The available evidence indicates that, both urinary and intestinal schistosomiasis are still highly endemic in Tanzania and cause significant morbidity.Mass drug administration using praziquantel, currently used as a key intervention measure, has not been successful in decreasing prevalence of infection. There is therefore an urgent need to revise the current approach for the successful control of the disease. Clearly, these need to be integrated control measures.
在坦桑尼亚,19 世纪初首次报告了血吸虫病病例。此后,各种研究报告称,在某些地区的患病率高达 100%。然而,多年来,这里一直没有可持续的控制规划,公共领域中可用于观察性和控制性研究的系统数据非常有限。为了填补这一空白,本文综述了坦桑尼亚血吸虫病的流行病学、贝类学、发病率,以及该国在努力控制血吸虫病方面取得的里程碑式进展,并讨论了未来的控制方法。现有证据表明,尿路和肠道血吸虫病在坦桑尼亚仍然高度流行,导致严重的发病率。目前,使用吡喹酮进行大规模药物治疗作为主要干预措施,并未成功降低感染率。因此,迫切需要修改当前的疾病控制方法。显然,这些都需要综合控制措施。