• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Interactions of Mn2+ with a non-self-complementary Z-type DNA duplex.锰离子（Mn2+）与非自互补Z型DNA双链体的相互作用。
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Dec 1;68(Pt 12):1420-6. doi: 10.1107/S1744309112041759. Epub 2012 Nov 14.
2
Sequence-dependent microheterogeneity of Z-DNA: the crystal and molecular structures of d(CACGCG).d(CGCGTG) and d(CGCACG).d(CGTGCG).Z-DNA的序列依赖性微异质性：d(CACGCG).d(CGCGTG)和d(CGCACG).d(CGTGCG)的晶体结构与分子结构
J Mol Biol. 1995 May 19;248(5):918-30. doi: 10.1006/jmbi.1995.9894.
3
Four highly pseudosymmetric and/or twinned structures of d(CGCGCG) extend the repertoire of crystal structures of Z-DNA.四种高度拟准对称和/或孪晶结构的 d(CGCGCG) 扩展了 Z-DNA 晶体结构的目录。
Acta Crystallogr D Struct Biol. 2017 Nov 1;73(Pt 11):940-951. doi: 10.1107/S2059798317014954. Epub 2017 Oct 30.
4
Atomic resolution structure of a chimeric DNA-RNA Z-type duplex in complex with Ba(2+) ions: a case of complicated multi-domain twinning.原子分辨率结构的嵌合 DNA-RNA Z 型双链体与 Ba(2+) 离子复合物：一个复杂的多域孪晶的例子。
Acta Crystallogr D Struct Biol. 2016 Feb;72(Pt 2):211-23. doi: 10.1107/S2059798315024365. Epub 2016 Jan 22.
5
Interaction between the Z-type DNA duplex and 1,3-propanediamine: crystal structure of d(CACGTG)2 at 1.2 A resolution.Z型DNA双链与1,3 - 丙二胺之间的相互作用：d(CACGTG)2在1.2埃分辨率下的晶体结构
Biochemistry. 2006 Jan 31;45(4):1200-11. doi: 10.1021/bi051569l.
6
Z-DNA crystallography .Z-DNA晶体学
Biopolymers. 1997;14(1):65-90. doi: 10.1002/(SICI)1097-0282(1997)44:1<65::AID-BIP5>3.0.CO;2-Y.
7
Ultrahigh-resolution crystal structures of Z-DNA in complex with Mn(2+) and Zn(2+) ions.与锰离子（Mn(2+)）和锌离子（Zn(2+)）结合的Z-DNA的超高分辨率晶体结构。
Acta Crystallogr D Biol Crystallogr. 2013 Jun;69(Pt 6):1180-90. doi: 10.1107/S0907444913007798. Epub 2013 May 16.
8
Ultrahigh-resolution centrosymmetric crystal structure of Z-DNA reveals the massive presence of alternate conformations.Z-DNA 的超高分辨率中心对称晶体结构揭示了大量的交替构象。
Acta Crystallogr D Struct Biol. 2016 Nov 1;72(Pt 11):1203-1211. doi: 10.1107/S205979831601679X. Epub 2016 Oct 28.
9
Structure of d(TGCGCG).d(CGCGCA) in two crystal forms: effect of sequence and crystal packing in Z-DNA.两种晶体形式下d(TGCGCG).d(CGCGCA)的结构：序列和晶体堆积对Z-DNA的影响
Acta Crystallogr D Biol Crystallogr. 2005 Aug;61(Pt 8):1125-31. doi: 10.1107/S0907444905016781. Epub 2005 Jul 20.
10
Structure of d(CACGCG).d(CGCGTG) in crystals grown in the presence of ruthenium III hexammine chloride.
Acta Crystallogr D Biol Crystallogr. 1998 Jul 1;54(Pt 4):501-9. doi: 10.1107/s0907444997013954.

引用本文的文献

1
Four highly pseudosymmetric and/or twinned structures of d(CGCGCG) extend the repertoire of crystal structures of Z-DNA.四种高度拟准对称和/或孪晶结构的 d(CGCGCG) 扩展了 Z-DNA 晶体结构的目录。
Acta Crystallogr D Struct Biol. 2017 Nov 1;73(Pt 11):940-951. doi: 10.1107/S2059798317014954. Epub 2017 Oct 30.
2
Phosphates in the Z-DNA dodecamer are flexible, but their P-SAD signal is sufficient for structure solution.Z-DNA十二聚体中的磷酸根具有灵活性，但其磷-硒反常散射信号足以用于解析结构。
Acta Crystallogr D Biol Crystallogr. 2014 Jul;70(Pt 7):1790-800. doi: 10.1107/S1399004714004684. Epub 2014 Jun 24.
3
Distinct Z-DNA binding mode of a PKR-like protein kinase containing a Z-DNA binding domain (PKZ).含 Z-DNA 结合域的 PKR 样蛋白激酶的独特 Z-DNA 结合模式（PKZ）。
Nucleic Acids Res. 2014 May;42(9):5937-48. doi: 10.1093/nar/gku189. Epub 2014 Mar 20.

本文引用的文献

1
Structure of the tetradecanucleotide d(CCCCGGTACCGGGG)2 as an A-DNA duplex.作为A-DNA双链体的十四聚体d(CCCCGGTACCGGGG)2的结构
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Apr 1;68(Pt 4):393-9. doi: 10.1107/S174430911200869X. Epub 2012 Mar 27.
2
REFMAC5 for the refinement of macromolecular crystal structures.用于大分子晶体结构精修的REFMAC5
Acta Crystallogr D Biol Crystallogr. 2011 Apr;67(Pt 4):355-67. doi: 10.1107/S0907444911001314. Epub 2011 Mar 18.
3
The interaction of manganese ions with DNA.锰离子与DNA的相互作用。
J Inorg Biochem. 2009 Jun;103(6):876-80. doi: 10.1016/j.jinorgbio.2009.03.004. Epub 2009 Mar 25.
4
Hexammineruthenium(III) ion interactions with Z-DNA.六氨合钌（III）离子与Z-DNA的相互作用。
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Dec 1;63(Pt 12):1008-13. doi: 10.1107/S1744309107047781. Epub 2007 Nov 21.
5
Structure of d(TGCGCG).d(CGCGCA) in two crystal forms: effect of sequence and crystal packing in Z-DNA.两种晶体形式下d(TGCGCG).d(CGCGCA)的结构：序列和晶体堆积对Z-DNA的影响
Acta Crystallogr D Biol Crystallogr. 2005 Aug;61(Pt 8):1125-31. doi: 10.1107/S0907444905016781. Epub 2005 Jul 20.
6
REFMAC5 dictionary: organization of prior chemical knowledge and guidelines for its use.REFMAC5词典：先前化学知识的组织及其使用指南。
Acta Crystallogr D Biol Crystallogr. 2004 Dec;60(Pt 12 Pt 1):2184-95. doi: 10.1107/S0907444904023510. Epub 2004 Nov 26.
7
Coot: model-building tools for molecular graphics.Coot：分子图形的模型构建工具。
Acta Crystallogr D Biol Crystallogr. 2004 Dec;60(Pt 12 Pt 1):2126-32. doi: 10.1107/S0907444904019158. Epub 2004 Nov 26.
8
Cobalt hexammine induced tautomeric shift in Z-DNA: the structure of d(CGCGCA)*d(TGCGCG) in two crystal forms.六氨合钴诱导Z-DNA中的互变异构移位：两种晶体形式的d(CGCGCA)*d(TGCGCG)的结构
Nucleic Acids Res. 2004 Nov 8;32(19):5945-53. doi: 10.1093/nar/gkh919. Print 2004.
9
Space-group degeneracy in the packing of a non-selfcomplementary Z-DNA hexamer.
Acta Crystallogr D Biol Crystallogr. 1994 Mar 1;50(Pt 2):192-6. doi: 10.1107/S0907444993011035.
10
3DNA: a software package for the analysis, rebuilding and visualization of three-dimensional nucleic acid structures.3DNA：一个用于三维核酸结构分析、重建和可视化的软件包。
Nucleic Acids Res. 2003 Sep 1;31(17):5108-21. doi: 10.1093/nar/gkg680.

锰离子（Mn2+）与非自互补Z型DNA双链体的相互作用。

Interactions of Mn2+ with a non-self-complementary Z-type DNA duplex.

作者信息

Mandal P K, Venkadesh S, Gautham N

机构信息

CAS in Crystallography and Biophysics, University of Madras, Guindy, Chennai 600 025, India.

出版信息

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Dec 1;68(Pt 12):1420-6. doi: 10.1107/S1744309112041759. Epub 2012 Nov 14.

DOI:10.1107/S1744309112041759
PMID:23192018
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3509959/
Abstract

Crystal structures of the hexanucleotide d(CACGCG)·d(CGCGTG) were determined in two crystal lattices when different concentrations of the counterion Mn2+ were used in crystallization. The availability of Mn2+ during the crystallization process appears to play an important role in inducing different crystal packings that lead to crystals belonging to the two space groups P2(1) and P6(5). Analysis of the molecular interactions of Mn2+ with the Z-form duplexes shows direct coordination to the purine residues G and A.

摘要

当在结晶过程中使用不同浓度的抗衡离子Mn2+时，在两个晶格中测定了六核苷酸d（CACGCG）·d（CGCGTG）的晶体结构。结晶过程中Mn2+的可用性似乎在诱导不同的晶体堆积中起重要作用，这些堆积导致晶体属于两个空间群P2(1)和P6(5)。对Mn2+与Z型双链体的分子相互作用分析表明，Mn2+与嘌呤残基G和A直接配位。