基于碳点的比率荧光传感器用于检测水相介质和活细胞内的硫化氢。
Carbon-dot-based ratiometric fluorescent sensor for detecting hydrogen sulfide in aqueous media and inside live cells.
机构信息
College of Materials Science & Engineering, State Key Lab of Luminescent Materials & Devices, South China University of Technology, Guangzhou 510640, China.
出版信息
Chem Commun (Camb). 2013 Jan 14;49(4):403-5. doi: 10.1039/c2cc37329g. Epub 2012 Nov 28.
PMID:23192384
Abstract
A FRET ratiometric fluorescent sensor was developed for detecting H(2)S in aqueous media and serum, as well as inside live cells. For this sensor, carbon dots serve as the energy donor and also the anchoring site for the probe. This sensor is highly selective and sensitive with a detection limit of 10 nM which is the lowest among fluorescent H(2)S sensors.
摘要
一种荧光共振能量转移（FRET）比率型荧光传感器被开发出来，用于检测水相介质和血清中的 H2S，以及活细胞内的 H2S。在该传感器中，碳点不仅作为能量供体，还作为探针的锚定位点。该传感器具有很高的选择性和灵敏度，检测限低至 10 nM，是荧光型 H2S 传感器中最低的。
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