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NCBI GEO：功能基因组学数据集存档 - 更新。

NCBI GEO: archive for functional genomics data sets--update.

机构信息

National Center for Biotechnology Information, National Library of Medicine and Molecular Genetics Section, Genetics Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

出版信息

Nucleic Acids Res. 2013 Jan;41(Database issue):D991-5. doi: 10.1093/nar/gks1193. Epub 2012 Nov 27.

DOI:10.1093/nar/gks1193
PMID:23193258
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3531084/
Abstract

The Gene Expression Omnibus (GEO, http://www.ncbi.nlm.nih.gov/geo/) is an international public repository for high-throughput microarray and next-generation sequence functional genomic data sets submitted by the research community. The resource supports archiving of raw data, processed data and metadata which are indexed, cross-linked and searchable. All data are freely available for download in a variety of formats. GEO also provides several web-based tools and strategies to assist users to query, analyse and visualize data. This article reports current status and recent database developments, including the release of GEO2R, an R-based web application that helps users analyse GEO data.

摘要

基因表达综合数据库（GEO，http://www.ncbi.nlm.nih.gov/geo/）是一个国际性的公共存储库，用于存储研究社区提交的高通量微阵列和下一代测序功能基因组数据集。该资源支持原始数据、处理后的数据和元数据的归档，这些数据被索引、交叉链接和可搜索。所有数据都以多种格式免费提供下载。GEO 还提供了几种基于网络的工具和策略，以帮助用户查询、分析和可视化数据。本文报告了当前的状态和最近的数据库发展情况，包括 GEO2R 的发布，这是一个基于 R 的网络应用程序，可帮助用户分析 GEO 数据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a6c/3531084/1221603f2b69/gks1193f2p.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a6c/3531084/1e1bd7cc1b6f/gks1193f1p.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a6c/3531084/1221603f2b69/gks1193f2p.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a6c/3531084/1e1bd7cc1b6f/gks1193f1p.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a6c/3531084/1221603f2b69/gks1193f2p.jpg

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本文引用的文献

[1]
An integrated encyclopedia of DNA elements in the human genome.

Nature. 2012-9-6

[2]
Gene data to hit milestone.

Nature. 2012-7-18

[3]
BioProject and BioSample databases at NCBI: facilitating capture and organization of metadata.

Nucleic Acids Res. 2011-12-1

[4]
Data archiving is a good investment.

Nature. 2011-5-19

[5]
NCBI GEO: archive for functional genomics data sets--10 years on.

Nucleic Acids Res. 2011-1

[6]
NCBI Epigenomics: a new public resource for exploring epigenomic data sets.

Nucleic Acids Res. 2011-1

[7]
ArrayExpress update--an archive of microarray and high-throughput sequencing-based functional genomics experiments.

Nucleic Acids Res. 2011-1

[8]
The NIH Roadmap Epigenomics Mapping Consortium.

Nat Biotechnol. 2010-10

[9]
Microarray analysis of spaceflown murine thymus tissue reveals changes in gene expression regulating stress and glucocorticoid receptors.

J Cell Biochem. 2010-5-15

[10]
Archiving next generation sequencing data.

Nucleic Acids Res. 2009-12-3

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