Najafipour H, Mirzazadeh A, Haghdoost Aa, Shadkam M, Afshari M, Moazenzadeh M, Nasri Hr, Masoomi M, Mirzaiepour F, Azimzadeh B Sarvar, Forood A, Bahreini F, Mahmoudi Mr, Sanjari M, Mohamadi T Malek, Banivaheb Gh, Naderi Ma, Kashanian Gh Moshtaghi, Afshar R Malekpour, Ghazanfari Z, Navadeh S, Esmaeili A Shah
Physiology Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Iran J Public Health. 2012;41(9):86-92. Epub 2012 Sep 1.
This article was to present the sampling and measurements methods and the main preliminary findings of the KERCADR cohort study (first round) in an urban and peri-urban setting, Kerman, southeastern Iran 2009-11.
5900 (3238 female) people aged between 15 to 75 years were recruited in the household survey by non-proportional to size one-stage cluster sampling. Trained internal specialists, general practitioners, clinical psychologists and dentists have assessed the study subjects by person-assisted questionnaires regarding different NCD risk factors including cigarette and opium smoking, physical activity, nutrition habits, anxiety, depression, obesity, hypertension and oral health. Blood samples were also collected for determining FBS, HbA1c, cholesterol and triglyceride. Weighted standardized prevalence estimates were calculated by STATA 10 survey analysis package.
The participation rate was more than 95% in all subgroups. Cigarette smoking (18.4% vs. 1.2%), opium use (17.8% vs. 3.0%) and triglyceridemia (16.1% vs. 12.0%) were significantly higher among men than women. In contrast, women were presented with higher level of sever anxiety (29.1% vs. 16.7%), obesity (16.8% vs. 9.2%), low-physical activity (45.1% vs. 39.2%) and uncontrolled diabetes (60.2% vs. 31.0%). More than 68% of all subjects have presented with moderate to severe gingival index scores.
The first round of the KERCADR cohort with sufficient sample size and response rate provided precise estimates for the main clinical and para-clinical NCD risk factors. These evidences need to be translated into public health interventions and monitored in the next rounds of the cohort.
本文旨在介绍2009 - 2011年在伊朗东南部克尔曼市城乡结合部开展的KERCADR队列研究(第一轮)的抽样和测量方法以及主要初步研究结果。
通过与规模不成比例的单阶段整群抽样,在家庭调查中招募了5900名年龄在15至75岁之间的人(3238名女性)。训练有素的内科专家、全科医生、临床心理学家和牙医通过个人辅助问卷对研究对象进行了评估,问卷涉及不同的非传染性疾病风险因素,包括吸烟和吸食鸦片、身体活动、营养习惯、焦虑、抑郁、肥胖、高血压和口腔健康。还采集了血样以测定空腹血糖、糖化血红蛋白、胆固醇和甘油三酯。使用STATA 10调查分析软件包计算加权标准化患病率估计值。
所有亚组的参与率均超过95%。男性吸烟率(18.4%对1.2%)、吸食鸦片率(17.8%对3.0%)和甘油三酯血症发生率(16.1%对12.0%)显著高于女性。相比之下,女性的严重焦虑水平(29.1%对16.7%)、肥胖率(16.8%对9.2%)、低身体活动率(45.1%对39.2%)和糖尿病未控制率(60.2%对31.0%)更高。超过68%的所有研究对象牙龈指数评分为中度至重度。
KERCADR队列研究的第一轮具有足够的样本量和应答率,为主要的临床和亚临床非传染性疾病风险因素提供了精确的估计值。这些证据需要转化为公共卫生干预措施,并在队列研究的后续轮次中进行监测。