Bartoszyński R, Powers J D
Department of Statistics, Ohio State University, Columbus 43210.
J Vet Pharmacol Ther. 1990 Mar;13(1):1-6. doi: 10.1111/j.1365-2885.1990.tb00740.x.
This paper presents a method of determining a confidence interval for the drug half-life based on statistical properties of the estimates of the disappearance rate constant of the drug. This interval is shown to be of minimum length which indicates it is a more precise estimate than others currently in use. A computer program to construct these intervals is available upon request.