Endow M, Suzuki H, Nakashima Y, Nagashima K, Tabata K, Tabata Y, Imanishi Y, Imamura K, Ishikawa T, Fujii M
Dept. of Radiology, St. Marianna Univ. School of Med.
Gan No Rinsho. 1990 Mar;36(4):505-13.
Reported are the results in 311 patients who received a multidisciplinary treatment for their cancers, said treatment combining hyperthermia, radiotherapy, and chemtherapy. Of his number, 266 patients were in the advance stage of their disease while another 42 still had localized cancers. According to the criteria of Koyama and Saitoh for evaluating solid tumors that had received chemotherapy, of 298 evaluable patients, 64 showed a complete response (CR), 94 showed a partial response (PR), 89 showed no change (NC), and 57 showed a progressive disease (PD), for an overall response of 53.0% (158 cases). A multidisciplinary treatment combining radiotherapy and hyperthermochemotherapy was used for cases involving localized tumors of the vulva, the skin, the thyroid gland, the prostate gland, the uterus, the rectum, the soft tissue bone, and the ovary, though our treatment regimen could not be continued in cases of tumors involving the stomach, the esophagus, the lung, the mediastinum, the liver, and the pancreas. Our data has shown that a high overall rate of curability was achieved in cases involving the stomach, the bladder, the blood, the skin, the head, and neck, and the esophagus.
报告了311例接受癌症多学科治疗患者的结果，该治疗结合了热疗、放疗和化疗。其中，266例患者处于疾病晚期，另有42例仍为局限性癌症。根据小山和斋藤评估接受化疗实体瘤的标准，在298例可评估患者中，64例显示完全缓解（CR），94例显示部分缓解（PR），89例显示无变化（NC），57例显示疾病进展（PD），总缓解率为53.0%（158例）。对于涉及外阴、皮肤、甲状腺、前列腺、子宫、直肠、软组织骨和卵巢的局限性肿瘤病例，采用了放疗和热化疗联合的多学科治疗，不过对于涉及胃、食管、肺、纵隔、肝和胰腺的肿瘤病例，我们的治疗方案无法继续。我们的数据表明，在涉及胃、膀胱、血液、皮肤、头颈部和食管的病例中，实现了较高的总体治愈率。
