Asaka Masahiro
Cancer Preventive Medicine, Hokkaido University, Graduate School of Medicine, Japan.
Nihon Rinsho. 2012 Oct;70(10):1667-72.
Gastric cancer screening by simultaneous measurement of serum pepsinogen and H. pylori antibody combined with eradication of H. pylori in all individuals at risk would initially increase national healthcare expenditure, but would eventually archive great savings by markedly reducing the cost of treating gastric cancer. The proposed strategy would prevent about 150,000 deaths from gastric cancer during the 5 years after its adoption. If the loss caused by these deaths is also taken into account, the economic effect of this strategy becomes enormous. It would probably reduce the incidence of gastric cancer by more than 80-90% within 10 years. The Japanese government should take the initiative to implement this strategy as soon as possible.
通过同时检测血清胃蛋白酶原和幽门螺杆菌抗体进行胃癌筛查，并对所有高危个体进行幽门螺杆菌根除治疗，最初会增加国家医疗保健支出，但最终会通过显著降低胃癌治疗成本实现巨大节省。所提议的策略在实施后的5年内可预防约15万例胃癌死亡。如果再考虑这些死亡造成的损失，该策略的经济效应将变得巨大。它可能在10年内将胃癌发病率降低80%至90%以上。日本政府应尽快主动实施这一策略。
