Yamada Masayoshi, Oda Ichiro, Taniguchi Hirokazu, Kushima Ryoji
Endoscopy Division, National Cancer Center Hospital.
Nihon Rinsho. 2012 Oct;70(10):1681-5.
In Japan, age-adjusted mortality rate of gastric cancer has decreased from 72.7 to 18.1 between 1960 and 2010 and the age-adjusted incidence rate of gastric cancer has decreased from 84.0 to 51.3 between 1975 and 2007. The National Cancer Center data of 20,250 resected gastric cancers shows the average age increased from 56 y/o to 64 y/o and the rate of endoscopic resection increased 0% to 44% between 1960's and 2000's. Histologically, intestinal type gastric cancer increased 41% to 68% and early gastric cancer also increased 22% to 75% at the same time. These changes can be contributed to a well-organized mass-screening system for gastric cancer and also advanced treatment techniques of endoscopy. When the next generation becomes of age for cancer age, in the following 20 to 30 years, clinicopathological characteristics of gastric cancer may change and it will become a relatively rare disease.
在日本,1960年至2010年间,胃癌的年龄调整死亡率从72.7降至18.1,1975年至2007年间,胃癌的年龄调整发病率从84.0降至51.3。国立癌症中心对20250例接受手术切除的胃癌病例的数据显示,1960年代至2000年代,患者的平均年龄从56岁增至64岁,内镜下切除术的比例从0%增至44%。从组织学上看,肠型胃癌同期从41%增至68%,早期胃癌也从22%增至75%。这些变化得益于完善的胃癌群体筛查系统以及先进的内镜治疗技术。当下一代达到癌症发病年龄时,在接下来的20至30年里,胃癌的临床病理特征可能会发生变化,它将成为一种相对罕见的疾病。