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[通过大规模筛查检测早期食管癌和胃癌]

[Detection of early esophageal and gastric cancers by mass screening].

作者信息

Mitsunaga N, Tsubouchi H

机构信息

Second Department of Internal Medicine, Miyazaki Medical College.

出版信息

Nihon Rinsho. 1996 May;54(5):1415-20.

PMID:8965377
Abstract

The purpose of mass screening is to decrease the mortality rate of diseases which are fatal if advanced by detecting them at an early and curable stage. From this point of view, we describe here the present state of mass screening, its problems, and the future of mass screening for esophageal and gastric cancer in Japan. The conventional X-ray examination commonly used to detect esophageal cancer does not seem to be effective in detecting the malignancy at an early stage. Therefore, endoscopic examination with Lugol staining for high-risk groups is recommended for the purpose. In contrast, mass screening for gastric cancer by X-ray examination, which has been applied until now, has reduced the mortality rate of gastric cancer. At the same time, however, as various problems are pointed out, some additional investigations have been undertaken to further reduce the mortality rate of gastric cancer. As social circumstances change, and therapy as well as diagnosis for the disease improves, it is necessary to evaluate the accuracy, problems, and limits of the present system to conduct effective and functional mass screening program. The present system must be adapted it to reflect improvements and changes.

摘要

大规模筛查的目的是通过在疾病早期可治愈阶段进行检测,降低那些若发展到晚期会致命的疾病的死亡率。从这一角度出发,我们在此阐述日本食管癌和胃癌大规模筛查的现状、存在的问题以及未来发展。常用于检测食管癌的传统X线检查似乎在早期检测恶性肿瘤方面效果不佳。因此,为此目的建议对高危人群进行卢戈氏染色内镜检查。相比之下,目前一直应用的通过X线检查进行的胃癌大规模筛查降低了胃癌死亡率。然而,与此同时,由于指出了各种问题,已开展了一些额外调查以进一步降低胃癌死亡率。随着社会环境的变化以及疾病治疗和诊断水平的提高,有必要评估当前系统的准确性、问题和局限性,以开展有效且实用的大规模筛查项目。必须对当前系统进行调整以反映改进和变化。

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