Gurav Abhijit N
Department of Periodontics, Tatyasaheb Kore Dental College & Research Centre, New Pargaon, Kolhapur 416137, Maharashtra, India.
Diabetes Metab Syndr. 2012 Oct-Dec;6(4):218-23. doi: 10.1016/j.dsx.2012.09.007. Epub 2012 Oct 24.
Periodontitis is an oral infection affecting the tooth- supporting tissues. Although the prime etiology for this condition is bacterial plaque, the host immune response also has substantial contribution to the destruction of the periodontal apparatus. Periodontitis elicits a "low grade systemic inflammation". Diabetes mellitus is intricately related to the development, progression and severity of periodontitis. The literature is abundant with studies depicting this association. Periodontal therapy (PT) involves removal of bacterial component leading to the resolution of clinical signs and symptoms of disease. This review aims to create awareness amongst the medical professionals regarding the two-way relationship between diabetes and periodontitis, emphasizing on the positive effects of PT.
Studies addressing the effects of PT on glycemic control in type 2 Diabetes (T2DM) subjects were identified using PubMed search with key search terms such as "Glycemic control", "Periodontitis", "Periodontal therapy", "Type 2 diabetes mellitus". The review has been prepared by screening PUBMED database from January 1990 to March 2012.
PT bears an unexplored potential and can serve as an adjuvant to the conventional treatment for diabetes.
A major conclusion of this review is that PT instituted in type 2 diabetic human subjects assists in amelioration of the inflammatory biomarker levels and glycemic status. There is a wide scope for further studies to highlight the beneficial effects of PT in diabetic subjects and the dire need for periodontal screening of these individuals for glycemic maintenance.
牙周炎是一种影响牙齿支持组织的口腔感染性疾病。尽管这种疾病的主要病因是细菌菌斑,但宿主免疫反应对牙周组织的破坏也有重要作用。牙周炎引发“低度全身炎症”。糖尿病与牙周炎的发生、发展及严重程度密切相关。文献中有大量研究描述了这种关联。牙周治疗(PT)包括去除细菌成分,从而使疾病的临床症状和体征得到缓解。本综述旨在提高医学专业人员对糖尿病与牙周炎双向关系的认识,强调牙周治疗的积极作用。
通过在PubMed数据库中使用“血糖控制”“牙周炎”“牙周治疗”“2型糖尿病”等关键词进行检索,确定了关于牙周治疗对2型糖尿病(T2DM)患者血糖控制影响的研究。本综述通过筛选1990年1月至2012年3月的PubMed数据库编制而成。
牙周治疗具有尚未被发掘的潜力,可作为糖尿病传统治疗的辅助手段。
本综述的一个主要结论是,对2型糖尿病患者进行牙周治疗有助于改善炎症生物标志物水平和血糖状况。进一步研究有很大空间来突出牙周治疗对糖尿病患者的有益作用,以及对这些个体进行牙周筛查以维持血糖水平的迫切需求。