Institute of Biomedical Engineering, National Yang Ming University, Taipei, Taiwan, ROC.
Injury. 2013 Jun;44(6):813-8. doi: 10.1016/j.injury.2012.10.017. Epub 2012 Nov 28.
The purpose of this study was to assess the efficacy of a new assistive procedure for injecting cement in percutaneous vertebroplasty (PV). Percutaneous vertebroplasty is frequently used for treating patients with osteoporotic vertebral compression fractures. However, the leakage of bone cement during PV may lead to serious complications, such as spinal cord compression or pulmonary embolism. Herein we present a secure procedure designed to safely and effectively deliver the bone cement into the vertebral column.
Thirty-five patients with a total of 50 levels of osteoporotic compression fracture were consecutively recruited for the study. During a routine PV operation, acrylic cement was injected with a simultaneous application of a continuous negative pressure to the contralateral side of the vertebral body. This negative pressure exerts a pulling force that attracts the bone cement to flow within the vertebral body.
With the proposed decompressed PV procedure, cross-filling of the vertebrographies was achieved for all 50 fracture levels, with no paravertebral venous plexus leakage. Three of the 50 levels (6%) exhibited contrast-medium leakage into the intradisc or cortical defect regions. After decompressed cement injection, excellent cross-filling of bone cement deposition was achieved in 38 of the 50 levels (76%; cement cross-filling region >75%), good cross-filling deposition was achieved in 7 levels (14%; cement cross-filling region >50%), deposition was poor in 3 levels (6%; cement cross-filling region <50%), and deposition failed in 2 levels (4%; fixed cement with no sign of cross-filling). Routine postoperative reviews revealed that six fracture levels (12%) had minimal cement leakage, with two leaking into the disc and four into paravertebral cortical defect regions.
Compared to the reported 20-88% cement leakage rate for the conventional PV procedure, the proposed decompressed PV procedure offers a more secure and effective way to perform cement injection, and reduces the likelihood of cement leakage.
本研究旨在评估一种新的经皮椎体成形术(PV)中注射水泥的辅助程序的疗效。经皮椎体成形术常用于治疗骨质疏松性椎体压缩性骨折患者。然而,PV 过程中骨水泥的渗漏可能导致严重并发症,如脊髓压迫或肺栓塞。在此,我们介绍了一种安全的程序,旨在安全有效地将骨水泥注入脊柱。
连续招募了 35 例共 50 个骨质疏松性压缩性骨折患者进行本研究。在常规 PV 手术中,向对侧椎体注射丙烯酸水泥,并施加持续的负压。这种负压产生拉力,吸引骨水泥在椎体内流动。
采用提出的减压 PV 程序,所有 50 个骨折水平均实现了椎体造影的交叉填充,无椎旁静脉丛渗漏。50 个水平中有 3 个(6%)出现对比剂漏入椎间盘或皮质缺损区域。减压后骨水泥注射后,38 个水平(76%;骨水泥交叉填充区域>75%)的骨水泥沉积实现了良好的交叉填充,7 个水平(14%;骨水泥交叉填充区域>50%)的交叉填充沉积良好,3 个水平(6%;骨水泥交叉填充区域<50%)沉积较差,2 个水平(4%;固定水泥无交叉填充迹象)沉积失败。常规术后复查显示,6 个骨折水平(12%)存在微小的水泥渗漏,其中 2 例漏入椎间盘,4 例漏入椎旁皮质缺损区。
与传统 PV 程序报告的 20-88%的水泥渗漏率相比,提出的减压 PV 程序提供了一种更安全有效的骨水泥注射方法,降低了水泥渗漏的可能性。