Suppr超能文献

[老年2型糖尿病的治疗]

[Treatment of type 2 diabetes in the elderly].

作者信息

Gómez Huelgas Ricardo, Díez-Espino Javier, Formiga Francesc, Lafita Tejedor Javier, Rodríguez Mañas Leocadio, González-Sarmiento Enrique, Menéndez Edelmiro, Sangrós Javier

机构信息

Sociedad Española de Medicina Interna (SEMI).

出版信息

Med Clin (Barc). 2013 Feb 2;140(3):134.e1-134.e12. doi: 10.1016/j.medcli.2012.10.003. Epub 2012 Nov 28.

Abstract

Treatment of type 2 diabetes in the elderly represents a major challenge both in terms of clinical management and public health. Aging is causing a marked increase in the pandemic of diabetes in elderly people. However, scientific evidence to support the most appropriate treatment for diabetes in the elderly is scarce. Given the heterogeneity of the elderly population, which includes subjects with very different functional and cognitive capacities, co-morbidities, and life expectancy, it is critical to make a comprehensive assessment from a biopsychosocial perspective, to address the vascular risk factors integrally, and to establish individually tailored targets for glycemic control. In frail elderly or individuals with a short life expectancy, it may be reasonable to maintain HbA1c between 7.6%-8.5%. The therapeutic strategy for elderly patients with type 2 diabetes should be individualized and agreed with the patient and their caregivers, according to the objective. Improving quality of life, assuring patient safety and avoiding the adverse effects of antidiabetic treatment should be prioritized. Given the increased susceptibility of the elderly to severe hypoglycemia and its consequences, antidiabetic therapies that minimize the risk of hypoglycemic events should be selected.

摘要

老年2型糖尿病的治疗在临床管理和公共卫生方面都是一项重大挑战。老龄化导致老年人群中糖尿病大流行显著增加。然而,支持老年糖尿病最适宜治疗方法的科学证据却很匮乏。鉴于老年人群的异质性,其中包括功能和认知能力、合并症及预期寿命差异很大的个体,从生物心理社会角度进行全面评估、整体解决血管危险因素并为血糖控制制定个体化目标至关重要。对于体弱的老年人或预期寿命较短的个体,将糖化血红蛋白(HbA1c)维持在7.6% - 8.5%之间可能是合理的。老年2型糖尿病患者的治疗策略应个体化,并根据目标与患者及其照护者达成一致。应优先提高生活质量、确保患者安全并避免抗糖尿病治疗的不良反应。鉴于老年人对严重低血糖及其后果的易感性增加,应选择能将低血糖事件风险降至最低的抗糖尿病疗法。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验