Department of Applied Genetics and Cell Biology, University of Natural Resources and Life Sciences, Vienna (BOKU), 1190 Vienna, Austria.
Curr Opin Plant Biol. 2013 Feb;16(1):78-84. doi: 10.1016/j.pbi.2012.10.005. Epub 2012 Nov 27.
The phytohormone auxin is an essential regulator for plant growth and development. Decades of intensive research revealed the mutual importance of auxin metabolism and intercellular cell-to-cell transport for the regulation of spatiotemporal auxin distribution. Just recently, intracellular putative auxin carriers, such as the PIN-FORMED (PIN)5/PIN8 and the PIN-LIKES (PILS)2/PILS5 were discovered at the endoplasmic reticulum (ER) and seem to limit nuclear auxin signaling via an auxin sequestration mechanism. Moreover, these auxin carriers at the ER might provide a link between auxin compartmentalization and auxin conjugation-based metabolism. Here we review the recent findings on auxin compartmentalization at the ER and discuss its potential contribution to cellular auxin homeostasis and its importance for plant development.
植物激素生长素是植物生长和发育的重要调节剂。数十年来的深入研究揭示了生长素代谢和细胞间细胞到细胞的运输对于调节时空生长素分布的相互重要性。就在最近，内质网（ER）中发现了细胞内假定的生长素载体，如 PIN 形成蛋白（PIN）5/PIN8 和 PIN 样蛋白（PILS）2/PILS5，它们似乎通过生长素隔离机制限制核生长素信号转导。此外，这些 ER 中的生长素载体可能为生长素区室化和基于生长素结合的代谢之间提供联系。在这里，我们回顾了内质网中生长素区室化的最新发现，并讨论了它对细胞内生长素稳态的潜在贡献及其对植物发育的重要性。
