Department of Oral and Maxillofacial Surgery, Division of Medicine, Interdisciplinary Graduate School of Medicine and Engineering University of Yamanashi, 1110 Shimokato, Chuo-shi,Yamanashi, Japan.
Int J Oral Maxillofac Surg. 2013 May;42(5):597-603. doi: 10.1016/j.ijom.2012.10.026. Epub 2012 Nov 28.
The purpose of this study was to compare retrospectively postoperative differences in maxillary stability after Le Fort I osteotomy and fixation with an unsintered hydroxyapatite (u-HA)/poly-l-lactic acid (PLLA) plate with or without self-setting α-tricalcium phosphate (Biopex(®)) as interpositional material. Subjects comprised 45 patients diagnosed with mandibular prognathism with maxillary retrognathism and mandibular prognathism with bimaxillary asymmetry. All patients underwent Le Fort I osteotomy and bilateral sagittal split ramus osteotomy with fixation by uHA/PLLA plates. Patients were divided into 4 groups consisting of 9 maxillary impaction cases with Biopex(®) (group 1) to fill the gap between the bone segments, 14 maxillary advancement cases with Biopex(®) (group 2), 8 maxillary impaction cases without Biopex(®) (group 3) and 14 maxillary advancement cases without Biopex(®) (group 4). Changes in cepahalometric parameters at time intervals (1, 3 and 12 months) between the groups were compared. Results showed that stability did not depend on the use or otherwise of Biopex(®).
本研究旨在比较回顾性研究 Le Fort I 截骨术后上颌骨稳定性的差异，比较使用和不使用未烧结羟基磷灰石（u-HA）/聚左旋乳酸（PLLA）板作为间隔材料的差异，以及使用或不使用自凝 α-磷酸三钙（Biopex(®)）的差异。研究对象包括 45 例诊断为下颌前突伴上颌后缩和双颌不对称的患者。所有患者均接受 Le Fort I 截骨术和双侧矢状劈开下颌骨截骨术，并用 uHA/PLLA 板固定。患者分为 4 组，每组 9 例上颌骨抬高伴 Biopex(®)（组 1），以填充骨段之间的间隙，14 例上颌骨前突伴 Biopex(®)（组 2），8 例上颌骨抬高不伴 Biopex(®)（组 3），14 例上颌骨前突不伴 Biopex(®)（组 4）。比较各组在时间间隔（1、3 和 12 个月）的头影测量参数变化。结果表明，稳定性不依赖于 Biopex(®)的使用与否。
