Suppr超能文献

正颌外科中的节段稳定性:羟基磷灰石/聚左旋乳酸骨传导复合材料与微型钛板骨合成术的比较

Segmental stability in orthognathic surgery: hydroxyapatite/Poly-l-lactide osteoconductive composite versus titanium miniplate osteosyntheses.

作者信息

Landes Constantin A, Ballon Alexander, Tran Andreas, Ghanaati Shahram, Sader Robert

机构信息

Department of Oral Maxillofacial and Plastic Facial Surgery, (Chair: Prof. Dr. Dr. Robert Sader), University Medical Centre Frankfurt/Main, Theodor-Stern-Kai 7, 60596 Frankfurt/Main, Germany.

Department of Oral Maxillofacial and Plastic Facial Surgery, (Chair: Prof. Dr. Dr. Robert Sader), University Medical Centre Frankfurt/Main, Theodor-Stern-Kai 7, 60596 Frankfurt/Main, Germany.

出版信息

J Craniomaxillofac Surg. 2014 Sep;42(6):930-42. doi: 10.1016/j.jcms.2014.01.013. Epub 2014 Jan 21.

Abstract

Hydroxyapatite was included into F-u-HA/PLLA (unsintered hydroxyapatite - Poly l-lactide) composite osteosynthesis material for its documented osteoconductive capacity. This study investigates segmental retention capacities and outcome stability using F-u-HA/PLLA composite osteosyntheses in orthognathic surgery. Of fifty patients in total, 25 patients were osteofixated with F-u-HA/PLLA osteoconductive bioabsorbable osteosyntheses and compared to a group of 25 patients treated with titanium miniplates. The F-u-HA/PLLA group included 14 maxillary advancements, 4 setbacks, 13 impactions, 5 elongations at A-point; the titanium group included 20 maxillary advancements, 2 setbacks, 11 impactions and 11 elongations. In the mandible the F-u-HA/PLLA group included 13 advancements at B-point, 11 setbacks, 16 clockwise rotations and 8 counterclockwise rotations at the Gonial angle (Ar-Go-Gn); the titanium group included 9 mandibular advancements, 5 setbacks, 8 clockwise rotations and 6 counterclockwise rotations at Ar-Go-Gn. Segmental stability and relapse were assessed comparing preoperative, postoperative and follow-up roentgen cephalometrics at 22 ± 11 months on average in F-u-HA/PLLA cases, 24 ± 22 months on average in the titanium group. All absolute operative movements were nonsignificant in the F-u-HA/PLLA cases compared to the titanium osteosynthesis cases. Relapses were nonsignificant but there was greater vertical relapse in maxillary impactions with titanium osteosyntheses. Throughout this study, F-u-HA/PLLA composite osteosyntheses appeared as stable as titanium miniplates. It can therefore be concluded, although from a limited number of patients, that the investigated osteoconductive osteosynthesis can be used in a similar way to titanium miniplates in orthognathic surgery. Compared to earlier studies using other bioabsorbable polymers in the literature, F-u-HA/PLLA proved to be more stable in segmental retention.

摘要

羟基磷灰石因其已被证实的骨传导能力而被纳入F-u-HA/PLLA(未烧结羟基磷灰石-聚左旋乳酸)复合骨合成材料中。本研究使用F-u-HA/PLLA复合骨合成术在正颌外科手术中研究节段保留能力和结果稳定性。在总共50例患者中,25例患者采用F-u-HA/PLLA骨传导性生物可吸收骨合成术进行骨固定,并与一组25例采用钛微型钢板治疗的患者进行比较。F-u-HA/PLLA组包括14例上颌前徙、4例后退、13例嵌入、5例A点伸长;钛组包括20例上颌前徙、2例后退、11例嵌入和11例伸长。在下颌骨中,F-u-HA/PLLA组包括13例B点前徙、11例后退、16例下颌角(Ar-Go-Gn)顺时针旋转和8例逆时针旋转;钛组包括9例下颌前徙、5例后退、8例Ar-Go-Gn顺时针旋转和6例逆时针旋转。通过比较术前、术后以及平均在F-u-HA/PLLA病例中22±11个月、钛组中24±22个月的随访头颅X线测量片来评估节段稳定性和复发情况。与钛骨合成病例相比,F-u-HA/PLLA病例中的所有绝对手术移动均无显著差异。复发情况无显著差异,但钛骨合成术在上颌嵌入病例中有更大的垂直复发。在整个研究中,F-u-HA/PLLA复合骨合成术与钛微型钢板一样稳定。因此可以得出结论,尽管患者数量有限,但所研究的骨传导性骨合成术在正颌外科手术中可以以与钛微型钢板类似的方式使用。与文献中早期使用其他生物可吸收聚合物的研究相比,F-u-HA/PLLA在节段保留方面更稳定。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验