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通过手术切除与PRGF-Endoret联合治疗双膦酸盐相关颌骨坏死（BRONJ）患者的半侧下颌感觉异常

Treatment of hemimandibular paresthesia in a patient with bisphosphonate-related osteonecrosis of the jaw (BRONJ) by combining surgical resection and PRGF-Endoret.

作者信息

Anitua E, Begoña L, Orive G

机构信息

Private Practice in Implantology and Oral Rehabilitation in Vitoria, Spain.

出版信息

Br J Oral Maxillofac Surg. 2013 Dec;51(8):e272-4. doi: 10.1016/j.bjoms.2012.08.018. Epub 2012 Nov 30.

DOI:10.1016/j.bjoms.2012.08.018
PMID:23201057
Abstract

We report a case of a 50-year-old patient with bisphosphonate-related osteonecrosis of the jaws (BRONJs) whose symptoms included severe pain and hemimandibular paraesthesia. The treatment included resection of necrotic bone and the application of plasma rich in growth factors (PRGF(®)-Endoret(®)). We closed the ulcer in the soft tissue and her pain and paraesthesia improved. One year postoperatively sensitivity was totally recovered, pain was absent and bone was partially regenerated.

摘要

我们报告一例50岁双膦酸盐相关颌骨骨坏死（BRONJs）患者，其症状包括严重疼痛和半侧下颌感觉异常。治疗包括切除坏死骨并应用富含生长因子的血浆（PRGF(®)-Endoret(®)）。我们封闭了软组织溃疡，患者的疼痛和感觉异常得到改善。术后一年，感觉完全恢复，疼痛消失，骨部分再生。

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