Department of Biochemistry and Molecular Biology, Thomas Jefferson University, 233 South 10th Street, Philadelphia, PA 19107, USA.
Cell. 2012 Dec 7;151(6):1148-50. doi: 10.1016/j.cell.2012.11.015. Epub 2012 Nov 29.
The 2012 Nobel Prize in Chemistry has been awarded to Brian K. Kobilka and Robert J. Lefkowitz for their studies of G-protein-coupled receptors. Their pioneering work over the past 40 years has provided detailed molecular insight into the structure and function of this fundamentally important family of receptors.
2012 年诺贝尔化学奖授予布莱恩·克比尔卡和罗伯特·莱夫科维茨,以表彰他们在 G 蛋白偶联受体方面的研究。他们在过去 40 年的开创性工作为这一基本重要的受体家族的结构和功能提供了详细的分子见解。