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[良性胃溃疡的病程;一项随访研究的结果]

[The course of benign stomach ulcer; results of a follow-up study].

作者信息

Drapers J A, Tytgat K M, Rauws E A, Tytgat G N

机构信息

Academisch Medisch Centrum, afd. Maag-, Darm- en Leverziekten, Amsterdam.

出版信息

Ned Tijdschr Geneeskd. 1990 Mar 31;134(13):643-7.

PMID:2320168
Abstract

A follow-up investigation was conducted in 112 patients in whom a benign gastric ulcer had been found endoscopically between 1978 and 1984. Nine patients had been operated upon, mainly in the earlier years. Out of 65 patients ultimately selected for the study 38 underwent gastroscopy and 35 could be evaluated. Of these 21 (60%) had complaints and another 60% used intermittent or continuous medication because of complaints referred to the stomach. In 15 patients erosions (4) or benign gastric ulcers (11) were found. In all patients in whom it was looked for Campylobacter pylori was found in the gastric mucosa. The benign gastric ulcer is a chronic, recurrent affection. We did not find a large proportion of asymptomatic recurrent ulcers. Many patients continue to use drugs. The complaints in patients with mucosal lesions are often atypical.

摘要

对1978年至1984年间经内镜检查发现患有良性胃溃疡的112例患者进行了随访调查。9例患者接受了手术,主要是在早期。最终入选该研究的65例患者中,38例接受了胃镜检查,35例可进行评估。其中21例(60%)有症状,另有60%因胃部相关症状使用了间歇性或持续性药物治疗。在15例患者中发现了糜烂(4例)或良性胃溃疡(11例)。在所有进行检测的患者的胃黏膜中均发现了幽门螺杆菌。良性胃溃疡是一种慢性复发性疾病。我们未发现大部分无症状复发性溃疡。许多患者继续使用药物。有黏膜病变的患者的症状往往不典型。

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