Takeuchi J, Takebe Y, Sakakura T, Hara Y, Yasuda T, Imai T
Department of Neurosurgery, Utano National Hospital, Kyoto, Japan.
Neurosurgery. 1990 Mar;26(3):499-503. doi: 10.1097/00006123-199003000-00018.
Autologous adrenal medulla was transplanted into the putamen of a patient with severe Parkinson's disease. After the operation, the patient's akinesia and rigidity decreased and the duration of action of L-dopa treatment was prolonged. The effect lasted for only 6 months, however, following which the patient's condition gradually began to deteriorate again, returning to the preoperative state by 12 months after surgery. This paper discusses possible reasons why the effect was only temporary.
将自体肾上腺髓质移植到一名重度帕金森病患者的壳核中。术后，患者的运动不能和强直症状减轻，左旋多巴治疗的作用持续时间延长。然而，这种效果仅持续了6个月，之后患者的病情又逐渐开始恶化，在手术后12个月时恢复到术前状态。本文讨论了效果仅为暂时的可能原因。
