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帕金森病中肾上腺髓质组织的立体定向移植

Stereotactic transplantation of adrenal medullary tissue in Parkinson's disease.

作者信息

Chung S S, Kim S H, Yoon D H

机构信息

Department of Neurosurgery, Yonsei University College of Medicine, Seoul, Korea.

出版信息

Stereotact Funct Neurosurg. 1990;54-55:272-6. doi: 10.1159/000100222.

Abstract

Autograft of adrenal medullary tissue into the striatum was performed stereotactically in 5 patients with severe Parkinson's disease. Two patients had suffered from side effects of L-dopa, and 3 were severely disabled without L-dopa preoperatively. After surgery, the dosage of L-dopa could be reduced in 1, and L-dopa could be withdrawn in 4 patients. The results of adrenal medullary tissue transplantation in Parkinson's disease are analyzed.

摘要

对5例重度帕金森病患者进行了立体定向肾上腺髓质组织自体移植。2例患者曾有左旋多巴副作用,3例术前未使用左旋多巴时严重致残。术后,1例患者左旋多巴用量可减少,4例患者可停用左旋多巴。对帕金森病肾上腺髓质组织移植的结果进行了分析。

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