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犬功能性单侧肾上腺皮质癌

Functioning unilateral adrenocortical carcinoma in a dog.

作者信息

Gójska-Zygner Olga, Lechowski Roman, Zygner Wojciech

机构信息

Centre of Small Animal Health, Clinic Multiwet, Warsaw, Poland.

出版信息

Can Vet J. 2012 Jun;53(6):623-5.

PMID:23204580
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3354820/
Abstract

An 11-year-old, 24-kg, intact female Siberian husky dog in anestrus had a 2-month history of polyuria and polydipsia. The dog had signs of mineralocorticoid excess such as hypertension and hypokalemia refractory to potassium supplementation. Abdominal ultrasound revealed an irregular mass in the left adrenal gland. The ACTH stimulation test for aldosterone concentration did not reveal hyperaldosteronism. Unilateral adrenalectomy was performed and histopathology identified adrenal cortical carcinoma. All clinical signs of mineralocorticoid excess ceased after surgery.

摘要

一只11岁、体重24千克、处于非发情期的未绝育雌性西伯利亚哈士奇犬,有2个月的多尿和多饮病史。该犬有盐皮质激素过多的体征,如高血压和补钾难以纠正的低钾血症。腹部超声显示左肾上腺有一个不规则肿块。醛固酮浓度的促肾上腺皮质激素刺激试验未显示醛固酮增多症。进行了单侧肾上腺切除术,组织病理学检查确诊为肾上腺皮质癌。术后盐皮质激素过多的所有临床体征均消失。

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Hypermineralocorticism without elevation of plasma aldosterone: deoxycorticosterone-producing adrenal adenoma and hyperplasia.血浆醛固酮未升高的高盐皮质激素血症:产生脱氧皮质酮的肾上腺腺瘤和增生。
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