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在晚期发现的髋关节脱位45年随访中,残余髋关节发育不良作为骨关节炎的一个危险因素。

Residual hip dysplasia as a risk factor for osteoarthritis in 45 years follow-up of late-detected hip dislocation.

作者信息

Terjesen Terje

机构信息

Orthopaedic Department, Rikshospitalet, Oslo University Hospital, 0027 Oslo, Norway.

出版信息

J Child Orthop. 2011 Dec;5(6):425-31. doi: 10.1007/s11832-011-0370-2. Epub 2011 Oct 7.

Abstract

PURPOSE

The aim of the study was to assess the role of residual hip dysplasia as a risk factor for osteoarthritis (OA) in developmental dysplasia of the hip (DDH).

METHODS

Fifty-one patients (60 hips) with late-detected DDH were studied. Reduction had been performed at a mean age of 19 months (range 4-65 months). On radiographs at age 8-10 years, at skeletal maturity, and at long-term follow-up, femoral head coverage was assessed using the migration percentage (MP) and centre-edge (CE) angle. OA was diagnosed if the minimum joint space width of the upper part of the joint was <2.0 mm.

RESULTS

The mean age at the last follow-up was 45 years (range 43-49 years) in patients who had not undergone total hip replacement (THR). Ten patients had developed OA and eight of them had undergone THR at a mean age of 40 years (range 32-47 years). There was a clear association between OA and residual hip dysplasia. At the last follow-up, 37 hips had normal CE angles (20° or higher) and OA had developed in only two of them (5%; 95% confidence interval [CI] 1-18%). Hip dysplasia without subluxation (CE angle 10-19°) was seen in 18 hips, of which 14 hips had good outcome and four had OA (22%; 95% CI 6-48%). Subluxation occurred in five hips, of which one had a good long-term outcome and four had OA (80%; 95% CI 28-99%). In patients without late reconstructive surgery, MP increased from the age of 10 years to skeletal maturity; thereafter, no significant change occurred. The CE angle did not change significantly between the age of 10 years and the last follow-up.

CONCLUSION

Hip dysplasia without subluxation has a relatively good long-term prognosis. Subluxation is a risk factor for osteoarthritis. Thus, children with MP above 33% and CE angle under 10° should be evaluated for reconstructive surgery in order to improve the long-term outcome.

摘要

目的

本研究旨在评估残留髋关节发育不良作为发育性髋关节发育不良(DDH)中骨关节炎(OA)危险因素的作用。

方法

对51例(60髋)晚发性DDH患者进行研究。复位手术平均年龄为19个月(范围4 - 65个月)。在8 - 10岁、骨骼成熟时及长期随访的X线片上,使用移位百分比(MP)和中心边缘(CE)角评估股骨头覆盖情况。若关节上部最小关节间隙宽度<2.0 mm,则诊断为OA。

结果

未接受全髋关节置换(THR)的患者最后一次随访时的平均年龄为45岁(范围43 - 49岁)。10例患者发生了OA,其中8例在平均年龄40岁(范围32 - 47岁)时接受了THR。OA与残留髋关节发育不良之间存在明显关联。在最后一次随访时,37髋CE角正常(20°或更高),其中仅2髋发生了OA(5%;95%置信区间[CI] 1 - 18%)。18髋可见无半脱位的髋关节发育不良(CE角10 - 19°),其中14髋预后良好,4髋发生了OA(22%;95% CI 6 - 48%)。5髋发生半脱位,其中1髋长期预后良好,4髋发生了OA(80%;95% CI 28 - 99%)。在未进行晚期重建手术的患者中,MP从10岁到骨骼成熟时增加;此后,无显著变化。10岁至最后一次随访期间,CE角无显著变化。

结论

无半脱位的髋关节发育不良长期预后相对较好。半脱位是骨关节炎的危险因素。因此,MP高于33%且CE角低于10°的儿童应评估是否进行重建手术,以改善长期预后。

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