Tangade Pradeep, Batra Manu
Department of Public Health Dentistry, Kothiwal Dental College & Research Centre, Kanth Road, Moradabad-244001, Uttar Pradesh, India.
Ethiop J Health Sci. 2012 Nov;22(3):219-21.
Oligodontia is a rare genetic disorder which represents the congenital absence of more than six teeth in primary, permanent or both dentitions. It is usually a part of a syndrome and seldom occurs as an isolated entity. Genes responsible for non syndromic oligodontia are found to be MSX1 and PAX9 genes. In this case report a 13 year old boy is presented who had absence of all four second permanent molars and permanent mandibular incisors. The maxillary central incisors presented with conical shape. During physical examination, there was no abnormality in either hairs or nails, perspiration was normal and no congenital clefts of lip or palate was seen. Hence in this case, Oligodontia is not associated with any syndrome which is a rare finding.
少牙畸形是一种罕见的遗传性疾病，表现为乳牙列、恒牙列或两者中先天性缺失超过六颗牙齿。它通常是综合征的一部分，很少作为孤立的病症出现。已发现导致非综合征性少牙畸形的基因是MSX1和PAX9基因。在本病例报告中，介绍了一名13岁男孩，他的四颗第二恒磨牙和下颌恒切牙全部缺失。上颌中切牙呈圆锥形。体格检查时，毛发和指甲均无异常，出汗正常，未见先天性唇腭裂。因此，在本病例中，少牙畸形与任何综合征均无关联，这是一个罕见的发现。
