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双侧髋关节假体前列腺癌患者调强放射治疗的受限束逆规划

Constrained-beam inverse planning for intensity-modulated radiation therapy of prostate cancer patients with bilateral hip prostheses.

作者信息

Martin Darren A, Hruby George, Whitaker May K, Foo Kerwyn Y-M

机构信息

Department of Radiation Oncology, Royal Prince Alfred Hospital, Camperdown, Australia.

出版信息

J Med Imaging Radiat Oncol. 2012 Dec;56(6):703-7. doi: 10.1111/j.1754-9485.2012.02456.x. Epub 2012 Oct 9.

DOI:10.1111/j.1754-9485.2012.02456.x
PMID:23210592
Abstract

Hip prostheses present a technical challenge in the planning of curative external beam radiation treatment for patients with prostate cancer. Bilateral prostheses compel planners to compromise between target coverage and avoidance of beam entry through the prostheses. Inverse planning systems given objectives to avoid dose to prostheses are overly restricted from allowing exit dose to them. We report a novel inverse planning technique for intensity-modulated radiation therapy of patients with prostate cancer and bilateral hip prostheses, by constraining beam characteristics rather than dose in the inverse planning process.

摘要

对于前列腺癌患者的根治性外照射放疗计划而言，髋关节假体带来了一项技术挑战。双侧假体迫使计划者在靶区覆盖和避免射线穿过假体之间做出妥协。给定避免对假体进行剂量照射目标的逆向计划系统，在允许射线从假体穿出剂量方面受到过度限制。我们报告了一种针对患有前列腺癌和双侧髋关节假体患者的调强放射治疗的新型逆向计划技术，即在逆向计划过程中通过约束射束特性而非剂量。

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