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三级护理足部诊所的抗生素处方集:使用肌内抗生素治疗糖尿病患者边缘性足部感染以避免住院。

An antibiotic formulary for a tertiary care foot clinic: admission avoidance using intramuscular antibiotics for borderline foot infections in people with diabetes.

机构信息

Diabetic Foot Clinic, Norfolk and Norwich University Hospitals NHS Foundation Trust, Colney Lane, Norwich, UK.

出版信息

Diabet Med. 2013 May;30(5):581-9. doi: 10.1111/dme.12074. Epub 2013 Feb 28.

Abstract

AIMS

To develop an antibiotic foot formulary for the empirical treatment of diabetes-related foot infections presenting to our service. Subsequently, to asses costs associated with the introduction of our protocol, in particular to assess the effect on admissions avoidance and any cost savings achieved.

METHODS

We reviewed several existing antibiotic protocols. We analysed data on costs related to treatment and admission rates prior to and after the introduction of the protocol.

RESULTS

We rationalized our antibiotic protocol and adapted the Infectious Disease Society of America guideline by introducing a category of 'moderate infection-borderline admission' to our classification. This enabled the administration of outpatient intramuscular antibiotics. After introducing the rationalized protocol, our average antibiotic prescribing costs for a 3-week course of treatment fell from £17.12 to £16.42. Over 22 months of follow-up, 26 episodes were eligible for treatment with intramuscular antibiotics. Over the same time period, 121 people were admitted directly from the foot clinic. The costs saved as a result of avoided or delayed admission for those 26 episodes was over £76 000. For 12 people who required subsequent admission, their length of hospital stay was significantly shorter than those admitted directly [9.25 days (range 2-25) vs. 16.11 (2-64), P = 0.045].

CONCLUSIONS

By modifying the Infectious Disease Society of America classification and adopting a protocol to administer outpatient oral and intramuscular antibiotics, we have led to substantial cost savings, shorter hospital admissions and also have developed a successful admissions avoidance strategy.

摘要

目的

为我们的服务中出现的糖尿病相关足部感染制定一个经验性治疗的抗生素足部处方。随后,评估引入我们的方案相关的成本,特别是评估对避免住院的影响和实现的任何成本节约。

方法

我们回顾了几种现有的抗生素方案。我们分析了引入方案前后与治疗和入院率相关的成本数据。

结果

我们合理化了我们的抗生素方案,并通过在我们的分类中引入“中度感染-边缘入院”类别来改编传染病学会的指南。这使得可以给予门诊肌肉内抗生素治疗。引入合理化方案后,我们 3 周疗程的平均抗生素处方费用从 17.12 英镑降至 16.42 英镑。在 22 个月的随访期间,有 26 个病例符合肌肉内抗生素治疗的条件。在同一时期,有 121 人直接从足部诊所入院。这 26 个病例避免或延迟入院所节省的费用超过 76000 英镑。对于需要后续入院的 12 人,他们的住院时间明显短于直接入院的患者[9.25 天(范围 2-25)与 16.11 天(范围 2-64),P=0.045]。

结论

通过修改传染病学会的分类并采用给予门诊口服和肌肉内抗生素的方案,我们实现了大量的成本节约、缩短了住院时间,并制定了成功的避免入院策略。

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