Couser Natario L, Lambert Scott R
Emory University Department of Ophthalmology, Atlanta, GA, USA.
Strabismus. 2012 Dec;20(4):158-61. doi: 10.3109/09273972.2012.702324.
To assess the outcome of botulinum A toxin (BTXA) to treat surgically overcorrected intermittent exotropia in children.
A retrospective analysis was performed on a series of children with consecutive esotropia treated with BTXA.
Six children with a mean consecutive esotropia of 21 prism diopters (PD) were treated with BTXA at a mean of 19.8 months following strabismus surgery. Two patients underwent a single injection, three patients 2 injections, and one patient 3 injections. Complications included transient ptosis and a vertical deviation. Mean follow-up from last BTXA injection was 16 months. At last follow-up, 4 of the 6 patients were orthotropic and stereopsis was present in 4 of 5 patients old enough to cooperate with testing. One patient was treated with strabismus surgery following a single BTXA injection.
BTXA is an efficacious treatment for consecutive esotropia in children. However, in our series, two-thirds of patients required multiple injections to achieve the desired outcome and one ultimately had an additional strabismus surgery.
评估A型肉毒杆菌毒素（BTXA）治疗儿童手术过度矫正的间歇性外斜视的效果。
对一系列接受BTXA治疗的连续性内斜视儿童进行回顾性分析。
6例平均连续性内斜视度数为21棱镜度（PD）的儿童在斜视手术后平均19.8个月接受了BTXA治疗。2例患者接受了单次注射，3例患者接受了2次注射，1例患者接受了3次注射。并发症包括短暂性上睑下垂和垂直斜视。自最后一次BTXA注射后的平均随访时间为16个月。在最后一次随访时，6例患者中有4例眼位正位，5例年龄足以配合检查的患者中有4例有立体视。1例患者在单次BTXA注射后接受了斜视手术。
BTXA是治疗儿童连续性内斜视的有效方法。然而，在我们的系列研究中，三分之二的患者需要多次注射才能达到预期效果，1例最终还接受了额外的斜视手术。
