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连续性外斜视发生的临床危险因素:一项对比临床研究。

Clinical risk factors for the development of consecutive exotropia: a comparative clinical study.

作者信息

Taylan Sekeroglu Hande, Erkan Turan Kadriye, Karakaya Jale, Sener Emin Cumhur, Sanac Ali Sefik

机构信息

Department of Ophthalmology, Hacettepe University Faculty of Medicine, Ankara 06100, Turkey.

Department of Biostatistics, Hacettepe University Faculty of Medicine, Ankara 06100, Turkey.

出版信息

Int J Ophthalmol. 2016 Jun 18;9(6):886-9. doi: 10.18240/ijo.2016.06.17. eCollection 2016.

Abstract

AIM

To compare a group of patients with consecutive exotropia with patients who had ≤10 prism diopters (PD) esotropia or no deviation postoperatively in terms of probable clinical risk factors for the development of consecutive exotropia.

METHODS

The study recruited fourteen patients who developed consecutive exodeviation during follow-up period after the correction of esotropia who were categorized as group 1 and thirty-one patients who had still ≤10 PD esotropia or no deviation at the final visit that were considered as group 2. Clinical risk factors leading the development of consecutive deviation were analyzed as the main outcome measures.

RESULTS

The mean age of patients was 4.57±3.11y in group 1 and 5.10±3.52y in group 2 (P=0.634). There was no significant difference of preoperative near and distant deviations among two groups (P=0.835, 0.928 respectively). The mean amount of medial rectus recession and lateral rectus resection was similar in both groups (P=0.412, 0.648 respectively). Convergence insufficiency and neurological diseases were more frequent in group 1 (P=0.007, 0.045). Accompanying neurological disease was found to be as a significant factor increasing the risk of the development of consecutive exotropia significantly [odds ratios (OR): 5.75 (1.04-31.93)].

CONCLUSION

Accompanying neurological disease appears to be a significant clinical risk factor for the development of consecutive exodeviation during postoperative follow-up after the correction of esotropia. However, larger studies are needed in order to interpret the results to the clinical practice and to ascertain other concurrent risk factors.

摘要

目的

比较一组连续性外斜视患者与术后内斜视度数≤10棱镜度(PD)或无斜视偏差的患者,分析可能导致连续性外斜视发生的临床危险因素。

方法

本研究招募了14例在矫正内斜视后的随访期间发生连续性外斜视偏差的患者,归为第1组;31例在最后一次随访时仍有≤10棱镜度内斜视或无斜视偏差的患者,归为第2组。分析导致连续性偏差发生的临床危险因素作为主要观察指标。

结果

第1组患者的平均年龄为4.57±3.11岁,第2组为5.10±3.52岁(P=0.634)。两组术前近、远距离斜视偏差无显著差异(分别为P=0.835、0.928)。两组内直肌后徙和外直肌缩短的平均量相似(分别为P=0.412、0.648)。第1组集合不足和神经系统疾病更为常见(P=0.007、0.045)。发现合并神经系统疾病是显著增加连续性外斜视发生风险的一个重要因素[优势比(OR):5.75(1.04-31.93)]。

结论

合并神经系统疾病似乎是内斜视矫正术后随访期间发生连续性外斜视偏差的一个重要临床危险因素。然而,需要更大规模的研究以便将结果应用于临床实践并确定其他并发危险因素。

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