Oregon Health and Science University, Portland, OR 97239-4501, USA.
Menopause. 2013 Apr;20(4):443-7. doi: 10.1097/gme.0b013e318275025e.
The purpose of this study was to assess the effect of soy isoflavone supplementation on quality of life in postmenopausal women.
A multicenter, randomized, double-blind, placebo-controlled 24-month trial was conducted to assess the effect of 80 or 120 mg of daily aglycone hypocotyl soy isoflavone supplementation on quality of life in 403 postmenopausal women using a validated Menopause-Specific Quality of Life questionnaire.
Menopause-Specific Quality of Life domain scores at 1 year and 2 years were similar to baseline. There were no differences in domain scores among treatment groups.
Soy isoflavone supplementation offers no benefit to quality of life in postmenopausal women.
本研究旨在评估大豆异黄酮补充剂对绝经后妇女生活质量的影响。
进行了一项多中心、随机、双盲、安慰剂对照的 24 个月试验，以评估每日 80 或 120 毫克苷元胚轴大豆异黄酮补充剂对 403 名绝经后妇女生活质量的影响，使用经过验证的绝经特异性生活质量问卷。
一年和两年的绝经特异性生活质量域评分与基线相似。治疗组之间的域评分没有差异。
大豆异黄酮补充剂对绝经后妇女的生活质量没有益处。
