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Severe obstructive sleep apnoea due to adenotonsillar hypertrophy after liver transplantation.肝移植后因腺样体扁桃体肥大导致的严重阻塞性睡眠呼吸暂停
BMJ Case Rep. 2012 Dec 4;2012:bcr2012007059. doi: 10.1136/bcr-2012-007059.
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本文引用的文献

1
Association between Epstein-Barr virus seroconversion and immunohistochemical changes in tonsils of pediatric solid organ transplant recipients.儿童实体器官移植受者的 EBV 血清转化与扁桃体免疫组织化学变化之间的关系。
Laryngoscope. 2011 Aug;121(8):1718-25. doi: 10.1002/lary.21871.
2
Tonsillectomy in post-transplant lymphoproliferative disease in children.儿童移植后淋巴组织增生性疾病的扁桃体切除术。
Laryngoscope. 2010 Mar;120(3):608-11. doi: 10.1002/lary.20799.
3
Adenotonsillar pathology in post-transplant patients.移植后患者的腺样体扁桃体病理学
Int J Pediatr Otorhinolaryngol. 2008 Jun;72(6):865-8. doi: 10.1016/j.ijporl.2008.02.016. Epub 2008 Apr 18.
4
Adenotonsillectomy in obstructive sleep apnea syndrome. Proposal of a surgical decision-taking algorithm.阻塞性睡眠呼吸暂停综合征的腺样体扁桃体切除术。手术决策算法建议。
Int J Pediatr Otorhinolaryngol. 2007 May;71(5):729-34. doi: 10.1016/j.ijporl.2007.01.007. Epub 2007 Feb 14.
5
Post-transplant lymphoproliferative disorder with supraglottic involvement.
B-ENT. 2005;1(1):53-6.
6
Risk factors for adenotonsillar hypertrophy in children following solid organ transplantation.实体器官移植后儿童腺扁桃体肥大的危险因素。
Int J Pediatr Otorhinolaryngol. 2003 Feb;67(2):151-5. doi: 10.1016/s0165-5876(02)00356-7.
7
Epstein-Barr virus infection in paediatric liver transplant recipients: detection of the virus in post-transplant tonsillectomy specimens.小儿肝移植受者的爱泼斯坦-巴尔病毒感染：移植后扁桃体切除标本中病毒的检测
Mol Pathol. 2001 Aug;54(4):264-9. doi: 10.1136/mp.54.4.264.
8
Adenotonsillar hypertrophy and Epstein-Barr virus in pediatric organ transplant recipients.小儿器官移植受者的腺样体扁桃体肥大与爱泼斯坦-巴尔病毒
Laryngoscope. 2001 Jun;111(6):997-1001. doi: 10.1097/00005537-200106000-00013.
9
The effectiveness of tonsillectomy in diagnosing lymphoproliferative disease in pediatric patients after liver transplantation.扁桃体切除术在诊断小儿肝移植术后淋巴增殖性疾病中的有效性。
Arch Otolaryngol Head Neck Surg. 2000 Dec;126(12):1444-7. doi: 10.1001/archotol.126.12.1444.
10
Adenotonsillar enlargement in pediatric patients following solid organ transplantation.实体器官移植后儿科患者的腺样体扁桃体增大
Arch Otolaryngol Head Neck Surg. 2000 Feb;126(2):159-64. doi: 10.1001/archotol.126.2.159.

肝移植后因腺样体扁桃体肥大导致的严重阻塞性睡眠呼吸暂停

Severe obstructive sleep apnoea due to adenotonsillar hypertrophy after liver transplantation.

作者信息

Mulla Omar, Bajaj Yogesh, Knight Lindsey

机构信息

Department of ENT Surgery, Leeds General Infirmary, Leeds, UK.

出版信息

BMJ Case Rep. 2012 Dec 4;2012:bcr2012007059. doi: 10.1136/bcr-2012-007059.

DOI:10.1136/bcr-2012-007059
PMID:23213127
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4544683/
Abstract

Epstein-Barr virus-related adenotonsillar hypertrophy is a precursor to post-transplantation lymphoproliferative disorder. We report a case of a 4-year-old child with severe obstructive sleep apnoea, who had liver transplantation at the age of 7 months. She had gross lymphoid hypertrophy in the oropharynx and supraglottis. We performed an adenotonsillectomy and aryepiglottoplasty which improved her symptoms. We emphasise the importance to consider the diagnosis of post-transplantation lymphoproliferative disorder in post-transplantation immunosuppressed patients who present with adenotonsillar hypertrophy.

摘要

爱泼斯坦-巴尔病毒相关的腺扁桃体肥大是移植后淋巴组织增生性疾病的前驱病变。我们报告一例4岁儿童，患有严重阻塞性睡眠呼吸暂停，7个月大时接受了肝移植。她的口咽和声门上有明显的淋巴样肥大。我们实施了腺扁桃体切除术和杓会厌成形术，症状得到改善。我们强调，对于出现腺扁桃体肥大的移植后免疫抑制患者，考虑诊断移植后淋巴组织增生性疾病的重要性。