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肝移植后因腺样体扁桃体肥大导致的严重阻塞性睡眠呼吸暂停

Severe obstructive sleep apnoea due to adenotonsillar hypertrophy after liver transplantation.

作者信息

Mulla Omar, Bajaj Yogesh, Knight Lindsey

机构信息

Department of ENT Surgery, Leeds General Infirmary, Leeds, UK.

出版信息

BMJ Case Rep. 2012 Dec 4;2012:bcr2012007059. doi: 10.1136/bcr-2012-007059.

Abstract

Epstein-Barr virus-related adenotonsillar hypertrophy is a precursor to post-transplantation lymphoproliferative disorder. We report a case of a 4-year-old child with severe obstructive sleep apnoea, who had liver transplantation at the age of 7 months. She had gross lymphoid hypertrophy in the oropharynx and supraglottis. We performed an adenotonsillectomy and aryepiglottoplasty which improved her symptoms. We emphasise the importance to consider the diagnosis of post-transplantation lymphoproliferative disorder in post-transplantation immunosuppressed patients who present with adenotonsillar hypertrophy.

摘要

爱泼斯坦-巴尔病毒相关的腺扁桃体肥大是移植后淋巴组织增生性疾病的前驱病变。我们报告一例4岁儿童,患有严重阻塞性睡眠呼吸暂停,7个月大时接受了肝移植。她的口咽和声门上有明显的淋巴样肥大。我们实施了腺扁桃体切除术和杓会厌成形术,症状得到改善。我们强调,对于出现腺扁桃体肥大的移植后免疫抑制患者,考虑诊断移植后淋巴组织增生性疾病的重要性。

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本文引用的文献

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Adenotonsillar pathology in post-transplant patients.移植后患者的腺样体扁桃体病理学
Int J Pediatr Otorhinolaryngol. 2008 Jun;72(6):865-8. doi: 10.1016/j.ijporl.2008.02.016. Epub 2008 Apr 18.

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