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一种非常有用的病原体,根癌农杆菌。

A really useful pathogen, Agrobacterium tumefaciens.

机构信息

Department of Microbiology and Immunology, University of Western Ontario.

出版信息

Plant Cell. 2012 Oct;24(10):tpc.112.tt1012. doi: 10.1105/tpc.112.tt1012.

Abstract

Bacteria of the genus Agrobacterium are very useful and unusual plant pathogens. Through a rare inter-kingdom DNA transfer, the bacteria move some of their genes into their host's genome, thereby inducing the host cells to proliferate and produce opines, nutrients sources for the pathogen. Agrobacterium's ability to transfer DNA makes can be adapted to introduce other genes, such as those encoding useful traits, into plant genomes. The development of Agrobacterium as a tool to transform plants is a landmark event in modern plant biology. This lecture provides an introduction to Agrobacterium tumefaciens and related species, focusing on their modes of pathogenicity, their usefulness as tools for plant transformation, and their use as a model for the study of plant-pathogen interactions.

摘要

根瘤农杆菌属的细菌是非常有用和不寻常的植物病原体。通过罕见的跨王国 DNA 转移,细菌将其部分基因转移到宿主的基因组中,从而诱导宿主细胞增殖并产生植物碱,这是病原体的营养来源。根瘤农杆菌转移 DNA 的能力可以被用来将其他基因,如编码有用性状的基因,引入植物基因组中。根瘤农杆菌作为一种转化植物的工具的发展是现代植物生物学的一个里程碑事件。本讲座介绍了根瘤农杆菌及其相关物种,重点介绍了它们的致病性模式、作为植物转化工具的用途以及作为研究植物-病原体相互作用的模型的用途。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/482b/3517252/9dc07f04acd7/tt1012fig1.jpg

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