Chen Zhong-Jie, Wu Zhong-Chao, Li Cai-Fen, Wang Qiao-Mei, Wang Jing-Jing, Pang Li, Wang Wen-Yan, Li Xin
Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Hospital of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Zhongguo Zhen Jiu. 2012 Nov;32(11):995-9.
To observe the impacts of different time of moxibustion on its regulating lipid effects and safety of hyperlipidemia.
Seventy-six cases of hyperlipidemia patients were randomly divided into three groups: including moxibustion 10 min group (group A, 25 cases), moxibustion 20 min group (group B, 25 cases) and moxibustion 30 min group (group C, 26 cases). All of these three groups choose the same acupoints, Shenque (CV 8),Zusanli (ST 36), Fenglong (ST 40) and Sanyinjiao (SP 6) were selected. These three groups were treated with moxibustion for 10 min, 20 min and 30 min, respectively, three times a week, 12 times constituted one course, two courses were required for each group. All indices of blood lipid and fasting blood glucose were observed before and after treatment, and the preliminary evaluation was made on the safety of hepatic and renal function.
There were significant decrease in total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C), and blood sugar after moxibustion treatment (all P<0.001), there was no significant difference of high density lipoprotein cholesterol (HDL-C) before and after treatment (P>0.05). The group C played more prominent role than group A in regulating the TC (P<0.01) and LDL-C (P<0.05), there was no significant difference between group C and group B (P>0.05). The blood urea nitrogen(BUN) was significantly reduced after moxibustion treatment (P<0.05), and there were no significant differences of other safety indices before and after treatment (all P>0.05).
Moxibustion can effectively and safely reduce the blood lipid level of hyperlipidemia patients, the decreasing degree of lipid is different with different time of moxibustion after treatment, and the decreasing degree in moxibustion 30 min group is significantly better than that in moxibustion 10 min group.
观察不同艾灸时间对高脂血症调脂作用及安全性的影响。
将76例高脂血症患者随机分为三组：艾灸10分钟组（A组，25例）、艾灸20分钟组（B组，25例）和艾灸30分钟组（C组，26例）。三组均选取相同穴位，选用神阙（CV 8）、足三里（ST 36）、丰隆（ST 40）和三阴交（SP 6）。三组分别给予艾灸10分钟、20分钟和30分钟，每周3次，12次为1个疗程，每组需治疗2个疗程。观察治疗前后血脂及空腹血糖各项指标，并对肝肾功能安全性进行初步评价。
艾灸治疗后总胆固醇（TC）、甘油三酯（TG）、低密度脂蛋白胆固醇（LDL-C）及血糖均显著降低（均P<0.001），治疗前后高密度脂蛋白胆固醇（HDL-C）差异无统计学意义（P>0.05）。C组在调节TC（P<0.01）和LDL-C（P<0.05）方面比A组作用更显著，C组与B组差异无统计学意义（P>0.05）。艾灸治疗后血尿素氮（BUN）显著降低（P<0.05），其他安全性指标治疗前后差异无统计学意义（均P>0.05）。
艾灸能有效、安全地降低高脂血症患者血脂水平，治疗后不同艾灸时间血脂下降程度不同，艾灸30分钟组下降程度显著优于艾灸10分钟组。
