Rubtsova N A, Novicova E G, Sinitsyn V E, Vostrov A N, Stepanov S O
Vestn Rentgenol Radiol. 2012 Jul-Aug(4):33-41.
to prospectively study and compare the capacities of magnetic resonance imaging (MRI) and ultrasound study (USS) in the preoperative assessment of the extent of endometrial cancer.
The study covered 50 patients with FIGO stages IA-IIIA endometrial cancer. A week before surgery, all the patients underwent small pelvic MRI and USS. The results of MRI and USS were compared with the data of a postoperative histological study.
The diagnostic value of MRI in preoperatively assessing the local extent of endometrial cancer was 82%, including its sensitivity, specificity, and accuracy; the prognostic value of a positive result and a negative one was as much as 94 and 56%, respectively. The accuracy, sensitivity, and specificity of USS were 70, 72, and 64%, respectively. Its prognostic value of a positive result and a negative one was 84 and 47%, respectively.
In this study, MRI versus USS showed a higher diagnostic efficiency in the preoperative staging in patients with endometrial cancer. The former promotes the optimization of assessment of the local extent of the tumor, including the depth of myometrial invasion and the spread into the cervix uteri, which affects the algorithm and policy of treatment for endometrial cancer.
前瞻性研究并比较磁共振成像(MRI)和超声检查(USS)在子宫内膜癌术前评估肿瘤范围方面的能力。
该研究纳入了50例国际妇产科联盟(FIGO)分期为IA-IIIA期的子宫内膜癌患者。术前一周,所有患者均接受盆腔MRI和USS检查。将MRI和USS的检查结果与术后组织学研究数据进行比较。
MRI术前评估子宫内膜癌局部范围的诊断价值为82%,包括其敏感性、特异性和准确性;阳性结果和阴性结果的预后价值分别高达94%和56%。USS的准确性、敏感性和特异性分别为70%、72%和64%。其阳性结果和阴性结果的预后价值分别为84%和47%。
在本研究中,MRI与USS相比,在子宫内膜癌患者术前分期中显示出更高的诊断效率。前者有助于优化对肿瘤局部范围的评估,包括肌层浸润深度和宫颈受累情况,这会影响子宫内膜癌的治疗方案和策略。