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[利用眼眶磁共振成像对格雷夫斯眼病的管理]

[Management of Graves' ophthalmopathy by using orbital magnetic resonance imaging].

作者信息

Hiromatsu Yuji, Eguchi Hiroyuki, Tani Junichi

机构信息

Division of Endocrinology and Metabolism, Department of Medicine, Kurume University School of Medicine.

出版信息

Nihon Rinsho. 2012 Nov;70(11):1932-7.

Abstract

Orbital magnetic resonance imaging (MRI) can visualize the inflamed lesions of Graves' ophthalmopathy(GO). Parasagittal, transverse and coronal sections of T1-weighted, T2-weighted and short inversion time inversion recovery(STIR) images correlate clinical manifestations with the location of the inflamed lesions. In addition, the measurement of T2 relaxation time or signal intensity ratio of the enlarged muscles in T2-weighted fat suppression images or STIR images provide a precise quantitative evaluation of disease activity and may predict the outcome of immunosuppressive therapy for GO. Thus, MRI is useful for decision-making regarding immunosuppressive therapy and prompt surgery for GO. Therefore, we recommend MRI as a useful tool for the management of GO in specialized clinics.

摘要

眼眶磁共振成像(MRI)能够显示格雷夫斯眼病(GO)的炎症性病变。T1加权、T2加权和短反转时间反转恢复(STIR)图像的矢状旁、横断和冠状面切片将临床表现与炎症性病变的位置相关联。此外,在T2加权脂肪抑制图像或STIR图像中测量眼外肌增粗的T2弛豫时间或信号强度比,可对疾病活动度进行精确的定量评估,并可预测GO免疫抑制治疗的效果。因此,MRI有助于GO免疫抑制治疗及及时手术的决策制定。所以,我们推荐将MRI作为专科诊所中GO管理的有用工具。

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