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[产后甲状腺功能障碍的概念与管理]

[Concept and management of postpartum thyroid dysfunction].

作者信息

Amino Nobuyuki, Ide Akane, Tamai Hidekazu

机构信息

Department of Internal Medicine, Kuma Hospital.

出版信息

Nihon Rinsho. 2012 Nov;70(11):1983-7.

Abstract

Postpartum thyroid dysfunction is found in 5-10% of women within one year after delivery. Dysfunction is developed from subclinical autoimmune thyroiditis through immune rebound mechanism and divided into 5 types. Most frequent one is destructive thyrotoxicosis, named as postpartum thyroiditis, which occur in early postpartum period and usually followed by transient hypothyroidism. Some of them progress into permanent hypothyroidism. Graves' disease is also developed mainly after 4 months postpartum and found in one out of 200 postpartum women in general population. Treatment of this dysfunction is principally the same as ordinal thyroid disease except for transient hypothyroidism.

摘要

产后甲状腺功能障碍在产后一年内的女性中发生率为5%-10%。该功能障碍由亚临床自身免疫性甲状腺炎通过免疫反弹机制发展而来,分为5种类型。最常见的是破坏性甲状腺毒症,即产后甲状腺炎,发生在产后早期,通常随后会出现短暂性甲状腺功能减退。其中一些会进展为永久性甲状腺功能减退。格雷夫斯病也主要在产后4个月后发病,在普通人群中,每200名产后女性中就有1例。除短暂性甲状腺功能减退外,这种功能障碍的治疗原则与普通甲状腺疾病相同。

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